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良性解剖变异:偶发瘤。

Benign anatomical mistakes: incidentaloma.

作者信息

Mirilas Petros, Skandalakis J E

机构信息

Centers for Surgical Anatomy and Technique, Emory University, Atlanta, Georgia 30322, USA.

出版信息

Am Surg. 2002 Nov;68(11):1026-8.

PMID:12455801
Abstract

The concept of the "incidentaloma," a totally asymptomatic nonfunctional tumor that is clinically and biochemically silent and discovered "incidentally" in a totally asymptomatic patient, is a by-product of the evolving diagnostic techniques of the last three decades. Various authors have used the concept for "incidental" findings during diagnostic workup for symptoms unrelated to adrenal disease, or for "incidental" adrenal tumors unrelated to symptoms that could potentially be of adrenal origin. "Incidentaloma" has been used to encompass a wide and heterogeneous spectrum of pathologic entities including adrenocortical and medullary tumors, benign or malignant lesions, hormonally active or inactive lesions, metastases, infections, granulomas, infiltrations, cysts and pseudocysts, hemorrhages, and pseudoadrenal masses. The term "incidentaloma" does not indicate whether the mass is functional, or malignant, or adrenocortical in origin. "Incidentaloma" has also appeared in the literature in reference to other endocrine organs such as pituitary, thyroid, and parathyroids, as well as the liver or kidney. We question the scientific justification for this neologism and suggest that it should be abolished. Questionable lesions should be clearly and simply described as "incidentally found."

摘要

“偶发瘤”这一概念指的是完全无症状的无功能肿瘤,在临床上和生化方面均无异常表现,是在完全无症状的患者中“偶然”发现的,它是过去三十年不断发展的诊断技术的产物。不同作者将这一概念用于与肾上腺疾病无关的症状的诊断检查过程中的“偶然”发现,或者用于与可能源于肾上腺的症状无关的“偶然”肾上腺肿瘤。“偶发瘤”已被用于涵盖广泛且异质性的一系列病理实体,包括肾上腺皮质和髓质肿瘤、良性或恶性病变、有激素活性或无激素活性的病变、转移瘤、感染、肉芽肿、浸润、囊肿和假性囊肿、出血以及假性肾上腺肿块。“偶发瘤”一词并未表明肿块是否有功能、是否为恶性或是否源于肾上腺皮质。“偶发瘤”在文献中也用于指代其他内分泌器官,如垂体、甲状腺和甲状旁腺,以及肝脏或肾脏。我们质疑这个新造词的科学合理性,并建议予以废除。有问题的病变应清晰简单地描述为“偶然发现”。

相似文献

1
Benign anatomical mistakes: incidentaloma.良性解剖变异:偶发瘤。
Am Surg. 2002 Nov;68(11):1026-8.
2
An evidence-based, multidisciplinary approach to the clinical considerations, management, and surveillance of adrenal lesions in familial adenomatous polyposis: report of three cases.家族性腺瘤性息肉病肾上腺病变的临床考量、管理及监测的循证多学科方法:三例报告
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Incidentally discovered masses in hypertensive patients.高血压患者中偶然发现的肿块
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4
[The adrenal incidentaloma: disease of modern era].[肾上腺偶发瘤:现代疾病]
Rev Med Suisse. 2009 Apr 8;5(198):774-8.
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[Pheochromocytomas as adrenal gland incidentalomas].[嗜铬细胞瘤作为肾上腺偶发瘤]
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Adrenal incidentaloma.肾上腺偶发瘤
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Nihon Rinsho. 2004 May;62(5):921-4.
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[Incidentally discovered adrenal masses in the Department of Internal Medicine, Endocrinology and Hemostatic Disorders, Medical University of Gdansk].[格但斯克医科大学内科、内分泌与止血障碍科偶然发现的肾上腺肿块]
Wiad Lek. 2006;59(11-12):744-50.
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[Adrenal incidentaloma: case report and synthesis of indication and thresholds of surgery therapy].[肾上腺偶发瘤:病例报告及手术治疗指征与阈值综述]
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[Incidentaloma--one of the greatest challenges of modern endocrinology].[偶发瘤——现代内分泌学的最大挑战之一]
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Prevalence and Features of Incidental Findings in Veterinary Computed Tomography: A Single-Center Six-Years' Experience.兽医计算机断层扫描中偶然发现的患病率及特征:单中心六年经验
Animals (Basel). 2023 Feb 8;13(4):591. doi: 10.3390/ani13040591.
2
Abdominal Ultrasound in the Detection of an Incidental Paraganglioma.腹部超声在偶然发现的副神经节瘤检测中的应用
J Med Ultrasound. 2020 Jul 14;29(2):119-122. doi: 10.4103/JMU.JMU_25_20. eCollection 2021 Apr-Jun.
3
Diagnosis, narrative identity, and asymptomatic disease.诊断、叙事身份与无症状疾病。
Theor Med Bioeth. 2017 Aug;38(4):307-321. doi: 10.1007/s11017-017-9412-1.
4
Calcitriol-mediated hypercalcemia in a patient with bilateral adrenal non-Hodgkin's B-cell lymphoma case report.一名双侧肾上腺非霍奇金B细胞淋巴瘤患者的骨化三醇介导的高钙血症病例报告
J Community Hosp Intern Med Perspect. 2016 Apr 25;6(2):30381. doi: 10.3402/jchimp.v6.30381. eCollection 2016.
5
Characterization of thyroid cancer in mouse models using high-frequency quantitative ultrasound techniques.利用高频定量超声技术对小鼠模型中的甲状腺癌进行特征描述。
Ultrasound Med Biol. 2013 Dec;39(12):2333-41. doi: 10.1016/j.ultrasmedbio.2013.07.006. Epub 2013 Sep 11.
6
Incidental findings on MRI of the temporomandibular joint.颞下颌关节磁共振成像的偶然发现。
Dentomaxillofac Radiol. 2013;42(10):20130175. doi: 10.1259/dmfr.20130175. Epub 2013 Sep 4.
7
Reflecting on earlier experiences with unsolicited findings: points to consider for next-generation sequencing and informed consent in diagnostics.反思早期在非预期发现方面的经验:下一代测序和诊断知情同意中的注意要点。
Hum Mutat. 2013 Oct;34(10):1322-8. doi: 10.1002/humu.22370. Epub 2013 Jul 16.
8
Secondary variants--in defense of a more fitting term in the incidental findings debate.次要变异——在偶然发现辩论中为一个更合适的术语辩护。
Eur J Hum Genet. 2013 Dec;21(12):1331-4. doi: 10.1038/ejhg.2013.89. Epub 2013 May 22.
9
Pituitary incidentalomas--how often is too often?垂体偶发瘤——多频繁才算过于频繁?
J Med Life. 2009 Jan-Mar;2(1):92-7.
10
Small renal masses: incidental diagnosis, clinical symptoms, and prognostic factors.小肾肿块:偶然诊断、临床症状及预后因素
Adv Urol. 2008;2008:310694. doi: 10.1155/2008/310694. Epub 2009 Jan 21.