Dispermy--origin of diandric triploidy: brief communication.

作者信息

McFadden Deborah E, Jiang Ruby, Langlois Sylvie, Robinson Wendy P

机构信息

Departments of Pathology and Medical Genetics, Children's and Women's Hospital of BC and University of British Columbia, Vancouver, BC V6H 3V4, Canada.

出版信息

Hum Reprod. 2002 Dec;17(12):3037-8. doi: 10.1093/humrep/17.12.3037.

DOI:10.1093/humrep/17.12.3037

PMID:12456599

Abstract

Triploidy may arise from either digynic or diandric fertilizations. Errors in the second meiotic division account for most digynic triploidy while most studies have found that approximately 2/3 of diandric triploids arise as the result of dispermy and 1/3 as the result of meiotic errors giving rise to diploid sperm. Using molecular markers very close to the centromere, all 14 cases of diandric triploidy were shown to be the result of dispermy with no evidence to support a meiotic error as the origin of diandric triploids.

摘要