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提高对药物相互作用的认识:使用自动药物警报的益处与障碍

Improving recognition of drug interactions: benefits and barriers to using automated drug alerts.

作者信息

Glassman Peter A, Simon Barbara, Belperio Pamela, Lanto Andrew

机构信息

VA HSR&D Center of Excellence for the Study of Healthcare Provider Behavior, VA Greater Los Angeles Healthcare System-West Los Angeles Campus, 11301 Wilshire Boulevard, Los Angeles, CA 90073, USA.

出版信息

Med Care. 2002 Dec;40(12):1161-71. doi: 10.1097/00005650-200212000-00004.

Abstract

BACKGROUND

Clinicians' perceptions about decision support systems may impact the effectiveness of these technologies.

OBJECTIVE

To explore clinicians' baseline knowledge of common drug interactions and experiences with automated drug alerts within a provider order entry system as a means to better understand the potential benefits and barriers to using this technology.

RESEARCH DESIGN

Cross-sectional survey.

SUBJECTS

The study population comprised 263 clinicians practicing within a Southern California Veterans Affairs health care system that used VA's Computerized Patient Record System (CPRS). Response rate was 64%.

MEASURES

A 67-item survey (19 questions) was developed to elicit information including: (1) computer use for patient-related activities; (2) recognition of drug interactions; and (3) benefits and barriers to using automated drug alerts.

RESULTS

Clinicians correctly categorized 44% (range 11-64%) of all drug-drug pairs, 53% of interacting combinations, and 54% of contraindicated pairs. Providers also correctly categorized 55% (range 24-87%) of 11 drug-disease pairs and 62% of interacting combinations, and 53% of contraindicated pairs. Nearly 90% of clinicians thought drug alerts would be helpful to identify interactions yet 55% of clinicians perceived that the most significant barrier to utilizing existing alerts was poor signal to noise ratio, meaning too many nonrelevant warnings.

CONCLUSIONS

Automated drug interaction alerts have the potential to dramatically increase clinicians' recognition of selected drug interactions. However, perceived poor specificity of drug alerts may be an important obstacle to efficient utilization of information and may impede the ability of such alerts to improve patient safety.

摘要

背景

临床医生对决策支持系统的看法可能会影响这些技术的有效性。

目的

探索临床医生对常见药物相互作用的基线知识以及在医嘱录入系统中使用自动药物警报的经验,以此更好地理解使用该技术的潜在益处和障碍。

研究设计

横断面调查。

研究对象

研究人群包括在南加州退伍军人事务医疗系统中执业的263名临床医生,该系统使用退伍军人事务部的计算机化患者记录系统(CPRS)。回复率为64%。

测量方法

设计了一份包含67个项目(19个问题)的调查问卷,以获取以下信息:(1)用于患者相关活动的计算机使用情况;(2)对药物相互作用的识别;(3)使用自动药物警报的益处和障碍。

结果

临床医生正确分类了所有药物对中的44%(范围为11%-64%)、相互作用组合中的53%以及禁忌对中的54%。医生们还正确分类了11种药物与疾病对中的55%(范围为24%-87%)、相互作用组合中的62%以及禁忌对中的53%。近90%的临床医生认为药物警报有助于识别相互作用,但55%的临床医生认为利用现有警报的最大障碍是信噪比低,即无关警告过多。

结论

自动药物相互作用警报有可能显著提高临床医生对特定药物相互作用的识别。然而,药物警报的特异性较差可能是有效利用信息的一个重要障碍,并且可能会妨碍此类警报提高患者安全的能力。

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