• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

脑和脊髓损伤后的恢复与再生策略。

Strategies for recovery and regeneration after brain and spinal cord injury.

作者信息

Tator C H

机构信息

University of Toronto and Toronto Western Hospital, ON Canada M5T 2S8.

出版信息

Inj Prev. 2002 Dec;8 Suppl 4(Suppl 4):IV33-6. doi: 10.1136/ip.8.suppl_4.iv33.

DOI:10.1136/ip.8.suppl_4.iv33
PMID:12460955
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1765495/
Abstract

Current knowledge of the epidemiology and pathophysiology of neurotrauma and the key clinical and experimental strategies for promoting recovery and regeneration after brain and spinal cord trauma are reviewed. Brief overviews of the epidemiology and pathophysiology of neurotrauma are presented, and the key experimental and clinical treatments for the promotion of recovery and regeneration after brain and spinal cord trauma are discussed.

摘要

本文回顾了神经创伤的流行病学和病理生理学的当前知识,以及促进脑和脊髓创伤后恢复和再生的关键临床和实验策略。介绍了神经创伤流行病学和病理生理学的简要概述,并讨论了促进脑和脊髓创伤后恢复和再生的关键实验和临床治疗方法。

相似文献

1
Strategies for recovery and regeneration after brain and spinal cord injury.脑和脊髓损伤后的恢复与再生策略。
Inj Prev. 2002 Dec;8 Suppl 4(Suppl 4):IV33-6. doi: 10.1136/ip.8.suppl_4.iv33.
2
Driving cognitive and motor gains with rehabilitation after brain and spinal cord injury.通过脑和脊髓损伤后的康复促进认知和运动功能恢复。
Curr Opin Neurol. 1998 Dec;11(6):639-41. doi: 10.1097/00019052-199812000-00005.
3
Strategies to promote regeneration and recovery in the injured spinal cord.促进脊髓损伤后再生与恢复的策略。
Neurosurg Clin N Am. 1990 Jul;1(3):751-9.
4
Functional rewiring of brain and spinal cord after injury: the three Rs of neural repair and neurological rehabilitation.
Curr Opin Neurol. 2000 Dec;13(6):655-9. doi: 10.1097/00019052-200012000-00007.
5
Spinal-cord injury.脊髓损伤
Lancet. 2002 Feb 2;359(9304):417-25. doi: 10.1016/S0140-6736(02)07603-1.
6
The costs of traumatic spinal cord and brain injuries in Wisconsin.威斯康星州创伤性脊髓损伤和脑损伤的费用。
Wis Med J. 1995;94(3):147-50.
7
Introduction: acquired central nervous system injuries.引言:获得性中枢神经系统损伤
Dev Disabil Res Rev. 2009;15(2):91-3. doi: 10.1002/ddrr.55.
8
Prediction of walking recovery after spinal cord injury.脊髓损伤后步行恢复的预测。
Brain Res Bull. 2009 Jan 15;78(1):43-51. doi: 10.1016/j.brainresbull.2008.06.002. Epub 2008 Jul 17.
9
Recovery from spinal cord injury: regeneration, plasticity and rehabilitation.脊髓损伤的恢复:再生、可塑性与康复
Brain. 2009 Jun;132(Pt 6):1417-8. doi: 10.1093/brain/awp121. Epub 2009 May 8.
10
Spinal cord injury medicine. 3. Rehabilitation phase after acute spinal cord injury.脊髓损伤医学。3. 急性脊髓损伤后的康复阶段。
Arch Phys Med Rehabil. 2007 Mar;88(3 Suppl 1):S62-70. doi: 10.1016/j.apmr.2006.12.003.

引用本文的文献

1
Neuroregenerative and neuroprotective effects of bioengineered scaffolds in spinal cord injury: a systematic review of preclinical and early phase clinical studies.生物工程支架在脊髓损伤中的神经再生和神经保护作用:对临床前和早期临床研究的系统评价
Spinal Cord. 2025 Aug 23. doi: 10.1038/s41393-025-01114-9.
2
Role of magnetic resonance imaging features in diagnosing and localization of disc rupture related to cervical spinal cord injury without radiographic abnormalities.磁共振成像特征在诊断及定位无放射学异常的颈脊髓损伤相关椎间盘破裂中的作用
Spinal Cord. 2023 Jun;61(6):323-329. doi: 10.1038/s41393-023-00886-2. Epub 2023 Mar 10.
3
Spinal cord extracts from injured spinal cord impede differentiation of rat embryonic neural stem cells into neurons through regulating Notch signaling pathway.来自损伤脊髓的脊髓提取物通过调节Notch信号通路阻碍大鼠胚胎神经干细胞向神经元分化。
Int J Clin Exp Pathol. 2019 Oct 1;12(10):3855-3861. eCollection 2019.
4
Functional recovery not correlated with axon regeneration through olfactory ensheathing cell-seeded scaffolds in a model of acute spinal cord injury.在急性脊髓损伤模型中,功能恢复与通过接种嗅鞘细胞的支架实现的轴突再生不相关。
Tissue Eng Regen Med. 2016 Oct 20;13(5):585-600. doi: 10.1007/s13770-016-9115-0. eCollection 2016 Oct.
5
Using NGF heparin-poloxamer thermosensitive hydrogels to enhance the nerve regeneration for spinal cord injury.使用神经生长因子肝素-泊洛沙姆热敏水凝胶增强脊髓损伤后的神经再生。
Acta Biomater. 2016 Jan;29:71-80. doi: 10.1016/j.actbio.2015.10.014. Epub 2015 Oct 22.
6
Nuclear translocation of PKM2 modulates astrocyte proliferation via p27 and -catenin pathway after spinal cord injury.脊髓损伤后,PKM2的核转位通过p27和β-连环蛋白途径调节星形胶质细胞增殖。
Cell Cycle. 2015;14(16):2609-18. doi: 10.1080/15384101.2015.1064203. Epub 2015 Jul 7.
7
Multivariate analysis of traumatic brain injury: development of an assessment score.创伤性脑损伤的多变量分析:一种评估评分的制定
Front Neurol. 2015 Mar 30;6:68. doi: 10.3389/fneur.2015.00068. eCollection 2015.
8
Ubiquitin carboxy-terminal hydrolase-l1 as a serum neurotrauma biomarker for exposure to occupational low-level blast.泛素羧基末端水解酶 -1作为职业性低强度爆炸暴露的血清神经创伤生物标志物。
Front Neurol. 2015 Mar 16;6:49. doi: 10.3389/fneur.2015.00049. eCollection 2015.
9
Current and future medical therapeutic strategies for the functional repair of spinal cord injury.脊髓损伤功能修复的当前及未来医学治疗策略
World J Orthop. 2015 Jan 18;6(1):42-55. doi: 10.5312/wjo.v6.i1.42.
10
Omega-conotoxin MVIIC attenuates neuronal apoptosis in vitro and improves significant recovery after spinal cord injury in vivo in rats.ω-芋螺毒素MVIIC可减轻体外培养的神经元凋亡,并显著促进大鼠脊髓损伤后的体内恢复。
Int J Clin Exp Pathol. 2014 Jun 15;7(7):3524-36. eCollection 2014.