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209例患者使用Beall人工心脏瓣膜进行二尖瓣置换的结果。

Results of mitral valve replacement with the Beall prosthesis in 209 patients.

作者信息

Fermandez J, Morse D, Spagna P, Lemole G, Gooch A, Yang S S, Maranhao V

出版信息

J Thorac Cardiovasc Surg. 1976 Feb;71(2):218-25.

PMID:1246147
Abstract

In this 3 year study of 209 patients who underwent mitral valve replacement with the newer Beall prostheses (Models 104 and 105) the operative mortality rate was 5.2 per cent. None of these deaths was related to the valve. This prosthesis features a larger frustrum area and a "turtle-neck" sewing ring which permits its rapid insertion with a continuous suture technique. Of the 20 (9.5 per cent) late deaths, two were due to thrombosis of the valve. Among the 178 survivors, 17 developed thromboembolic complications; however, 10 of these patients recovered. Late clinical results have been quite satisfactory in over 90 per cent of the survivors. In the 15 patients who underwent hemodynamic studies postoperatively, the cardiac index and pulmonary artery pressure showed significant improvement; however, they still had transvalvular gradients at rest. The improvement in the design of this prosthesis has been an important factor in lowering the operative risk and improving the late results of mitral valve replacement.

摘要

在这项针对209例接受新型Beall人工瓣膜(型号104和105)二尖瓣置换术患者的为期3年的研究中,手术死亡率为5.2%。这些死亡病例均与瓣膜无关。这种人工瓣膜的特点是有较大的截头圆锥体面积和一个“高领”缝合环,这使得它能够通过连续缝合技术快速植入。在20例(9.5%)晚期死亡病例中,2例死于瓣膜血栓形成。在178名幸存者中,17例出现血栓栓塞并发症;然而,其中10例患者康复。超过90%的幸存者的晚期临床结果相当令人满意。在15例术后接受血流动力学研究的患者中,心脏指数和肺动脉压有显著改善;然而,他们在静息状态下仍有跨瓣膜压差。这种人工瓣膜设计的改进是降低手术风险和改善二尖瓣置换术晚期结果的一个重要因素。

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