瑞士腹泻患者中产志贺毒素大肠杆菌

Verocytotoxin-producing Escherichia coli in patients with diarrhoea in Switzerland.

作者信息

Schmid H, Burnens A P, Baumgartner A, Boerlin P, Bille J, Liassine N, Friderich P, Breer C

机构信息

Division of Epidemiology and Infectious Diseases, Swiss Federal Office of Public Health, 3003 Bern, Switzerland,

出版信息

Eur J Clin Microbiol Infect Dis. 2002 Nov;21(11):810-3. doi: 10.1007/s10096-002-0829-7. Epub 2002 Nov 7.

DOI:10.1007/s10096-002-0829-7

PMID:12461591

Abstract

The present study was conducted between October 1996 and October 1998 to estimate the frequency of verocytotoxin-producing Escherichia coli among outpatients with diarrhoea in Switzerland. Among 3,041 subjects studied, 16 (0.5%) verocytotoxin-producing Escherichia coli infections were identified. Eleven cases were in infants and children </= 6 years of age. In 15 cases, a verocytotoxin-producing Escherichia coli strain was isolated. These strains belonged to 11 different serotypes, and only two were serogroup O157. In five cases, the infection was probably acquired outside Switzerland. Verocytotoxin-producing Escherichia coli apparently play a minor role in the aetiology of diarrhoeal disease in adult outpatients in Switzerland, but they are important pathogens in preschool children in whom the most severe symptoms are observed.

摘要

本研究于1996年10月至1998年10月进行，旨在评估瑞士腹泻门诊患者中产志贺毒素大肠杆菌的感染率。在3041名研究对象中，确诊了16例（0.5%）产志贺毒素大肠杆菌感染。其中11例为6岁及以下婴幼儿。15例中分离出产志贺毒素大肠杆菌菌株。这些菌株分属11种不同血清型，仅两种属于O157血清群。5例感染可能是在瑞士境外获得。产志贺毒素大肠杆菌在瑞士成年门诊腹泻患者病因中似乎起次要作用，但在学龄前儿童中却是重要病原体，这些儿童会出现最严重的症状。