Ali Muhammad Shaiq, Saleem Muhammad, Yamdagni Raghav, Ali Muhammad Ashfaq
HEJ Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan.
Nat Prod Lett. 2002 Dec;16(6):407-13. doi: 10.1080/10575630290034249.
The ethyl acetate soluble part of methanolic extract of marine green alga Codium iyengarii collected from Karachi coast of Arabian Sea afforded a new steroid ([structure: see text], iyengadione) and two new steroidal glycosides [iyengaroside-A ([structure: see text]) and B ([structure: see text])] along with clerosterol galactoside ([structure: see text]). Their structures were elucidated with the aid of 1D-NMR spectroscopy and reconfirmed through HMBC experiments. The bactericidal activity of [structure: see text] was also explored and found positive response from iyengaroside-A ([structure: see text]) and clerosterol galactoside ([structure: see text]).
从阿拉伯海卡拉奇海岸采集的海洋绿藻伊氏松藻甲醇提取物的乙酸乙酯可溶部分得到了一种新的甾体化合物([结构:见原文],伊氏松藻二酮)和两种新的甾体糖苷[伊氏松藻糖苷 -A([结构:见原文])和B([结构:见原文])],以及麦角甾醇半乳糖苷([结构:见原文])。借助一维核磁共振光谱阐明了它们的结构,并通过异核多键相关实验进行了重新确认。还探索了[结构:见原文]的杀菌活性,发现伊氏松藻糖苷 -A([结构:见原文])和麦角甾醇半乳糖苷([结构:见原文])有阳性反应。