Hälbig Thomas D, Yves von Cramon D, Schmid Urs D, Gall Claudius, Friederici Angela D
Max-Planck-Institute of Cognitive Neuroscience, Leipzig, Germany.
Brain Cogn. 2002 Nov;50(2):282-303. doi: 10.1016/s0278-2626(02)00514-6.
This study aimed to test the hypothesis that impairments of temporal duration processing after frontal lobe lesions reflect deficits in executive monitoring functions rather than a domain-specific deficit in the maintenance of duration information in working memory. Patients with frontodorsal lesions, clinical controls with post-central lesions, and healthy controls performed recognition and classification tasks, which should allow for testing maintenance and monitoring functions, respectively. Results showed mild non-selective impairments of the frontal patients on both temporal and spatial recognition tasks, but a marked selective degradation on temporal classification while performance on spatial classification was unimpaired. This suggests that maintenance of duration information in working memory after frontal lesions is basically preserved but that, depending on executive task characteristics, there is a specific deficit in the strategic organization of this type of information.
额叶损伤后时间持续加工的损害反映了执行监控功能的缺陷，而非工作记忆中持续信息维持方面的特定领域缺陷。额背侧损伤患者、中央后回损伤的临床对照者以及健康对照者进行了识别和分类任务，分别用于测试维持和监控功能。结果显示，额叶损伤患者在时间和空间识别任务上均有轻度非选择性损害，但在时间分类上有明显的选择性退化，而空间分类表现未受损害。这表明额叶损伤后工作记忆中持续信息的维持基本得以保留，但根据执行任务的特点，在这类信息的策略性组织方面存在特定缺陷。
