Ziaja Jacek, Wullstein Christoph, Woeste Guido, Bechstein Wolf Otto
Department of Surgery, Ruhr-University Bochum, Knappschaftskrankenhaus Bochum-Langendreer, Germany.
Ann Transplant. 2002;7(3):46-9.
One of the key issues in successful pancreas transplantation is uncomplicated drainage of pancreas exocrine secretion.
The aim of the study is to present results of side-to-side high duodeno-jejunal anastomosis as routine method of enteric drainage in simultaneous pancreas kidney transplantation (SPK).
30 diabetic patients underwent SPK at the Department of Surgery, Ruhr University Bochum in 2001. The pancreas was drained using a portion of duodenal segment anastomosed to the first loop of jejunum about 20-40 cm distal to the Treitz ligament.
Early relaparotomy was required in 20% patients. The mean time of first relaparotomy was 5.5 (range 1-11) days after transplantation. In 10% of cases graft pancreatectomy was necessary. Perioperative mortality was 3.3%. Currently 83.3% patients are insulin-free and 86.6% patients are free of dialysis.
These data suggest, that side-to-side high duodeno-jejunal anastomosis is a safe method of drainage of pancreas exocrine secretion in SPK.
成功进行胰腺移植的关键问题之一是胰腺外分泌的无并发症引流。
本研究的目的是展示侧侧高位十二指肠空肠吻合术作为同期胰肾联合移植（SPK）中肠内引流常规方法的结果。
2001年，30例糖尿病患者在波鸿鲁尔大学外科接受了SPK。胰腺采用十二指肠段的一部分与距屈氏韧带约20 - 40厘米远的空肠第一袢进行吻合来引流。
20%的患者需要早期再次剖腹手术。首次再次剖腹手术的平均时间为移植后5.5（范围1 - 11）天。10%的病例需要进行移植胰腺切除术。围手术期死亡率为3.3%。目前，83.3%的患者无需胰岛素治疗，86.6%的患者无需透析。
这些数据表明，侧侧高位十二指肠空肠吻合术是SPK中胰腺外分泌引流的一种安全方法。
