克雅氏病：一项光镜、组织化学及电镜比较研究
Creutzfeldt-jacob disease: a comparative light-microscopic, histochemical and electron-microscopic study.
作者信息
De Reuck J, De Coster W, vander Eecken H, Daneels P
出版信息
Eur Neurol. 1975;13(2):154-66. doi: 10.1159/000114671.
PMID:124655
Abstract
The morphological and histochemical findings in a brain biopsy of a case of Creutzfeldt-Jacob disease are compared. The histochemical changes in the cytoplasm of the neurons precede the morphological alterations found with the electron microscope. In this way the neuronal enzymatic failure can explain the clinical picture of this disease.
摘要
对一例克雅氏病患者脑活检的形态学和组织化学结果进行了比较。神经元细胞质中的组织化学变化先于电子显微镜下发现的形态学改变。通过这种方式，神经元酶功能衰竭可以解释这种疾病的临床表现。
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