Apkon Susan D
Department of Rehabilitation Medicine, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, A040, Denver, CO, USA.
Phys Med Rehabil Clin N Am. 2002 Nov;13(4):839-55. doi: 10.1016/s1047-9651(02)00026-8.
Children who have disabilities are at increased risk for osteoporosis during childhood. This not only puts them at risk for fractures during childhood but also during adulthood. Peak bone mass, which helps predict osteoporosis in adulthood, is never attained in children who have a disability. Care providers of this group of children must be aggressive in the prevention and treatment of osteoporosis. A thorough laboratory evaluation and DXA studies may be undertaken on all disabled children who are at risk for osteoporosis. Although medications have shown promise in the treatment of decreased bone mass, their efficacy in children who have disabilities must be evaluated in larger, controlled studies. Nonpharmocologic treatments also necessitate further exploration.
残疾儿童在童年时期患骨质疏松症的风险增加。这不仅使他们在童年时期有骨折风险，成年后也有此风险。有助于预测成年后骨质疏松症的骨峰值，残疾儿童从未达到过。这类儿童的护理人员必须积极预防和治疗骨质疏松症。对于所有有骨质疏松症风险的残疾儿童，可进行全面的实验室评估和双能X线吸收测定研究。尽管药物在治疗骨量减少方面已显示出前景，但它们对残疾儿童的疗效必须在更大规模的对照研究中进行评估。非药物治疗也需要进一步探索。
