在富电子杂原子存在下，二碘化钐促进的醛氧化反应。
SmI(2)-promoted oxidation of aldehydes in the presence of electron-rich heteroatoms.
作者信息
Smith Amos B, Lee Dongjoo, Adams Christopher M, Kozlowski Marisa C
机构信息
Department of Chemistry, Laboratory for Research on the Structure of Matter, Monell Chemical Senses Center, Philadelphia, Pennsylvania 19104, USA.
出版信息
Org Lett. 2002 Dec 12;4(25):4539-41. doi: 10.1021/ol027095p.
PMID:12465932
Abstract
[reaction: see text] The Evans-Tishchenko reaction provides an efficient and practical solution for the oxidation of aldehydes possessing sensitive electron-rich heteroatoms to the corresponding esters. Careful selection of the sacrificial beta-hydroxy ketone provides considerable subsequent flexibility to access the desired carboxylic acid.
摘要
[反应：见正文] 伊文斯-季先科反应为将含有敏感富电子杂原子的醛氧化为相应的酯提供了一种高效且实用的方法。仔细选择牺牲性β-羟基酮可为获得所需的羧酸提供相当大的后续灵活性。
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