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通过在膜中用麦角甾醇替代胆固醇来改变红细胞(见文章)-ATP酶。

Alteration of erythrocyte (see article) -ATPase by replacement of cholesterol by desmosterol in the membrane.

作者信息

Fiehn W, Seiler D

出版信息

Experientia. 1975 Jul 15;31(7):773-5. doi: 10.1007/BF01938456.

Abstract

Cholesterol of red blood cells (RBC) is readily exchanged by desmosterol and vice versa. The resulting alteration in the sterol composition influences the specific (Na+ plus K+)-ATPase activity. It is suggested that this effect is due to an altered membrane fluidity.

摘要

红细胞(RBC)中的胆固醇很容易与去氢胆固醇相互交换,反之亦然。由此产生的固醇组成变化会影响特定的(钠加钾)-ATP酶活性。有人认为这种效应是由于膜流动性改变所致。

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本文引用的文献

5
A spin label study of sarcoplasmic vesicles.
Eur J Biochem. 1971 Jul 15;21(1):17-21. doi: 10.1111/j.1432-1033.1971.tb01434.x.
7
Influence of altered sterol composition on (Na+, K+) ATPase activity of cardiac sarcolemma.
Experientia. 1974 Dec 15;30(12):1421-2. doi: 10.1007/BF01919672.
8
ATPases of erythrocytes from rats with 20, 25-diazacholesterol induced myotonia.
FEBS Lett. 1973 Aug 15;34(2):163-4. doi: 10.1016/0014-5793(73)80783-5.

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