Delany H M, Moss C M, Carnevale N
Surg Gynecol Obstet. 1976 Feb;142(2):167-7.
Seventy patients with blunt and penetrating abdominal trauma and hemoperitoneum were evaluated by the analysis of the enzyme content of peritoneal blood using automated laboratory methods. The enzyme levels in peritoneal blood were evaluated relative to the simultaneous levels in peripheral blood to identify enzyme differences in organ-related peritoneal and periheral blood. The findings in this study indicate that isolated liver injuries are associated with significant elevation of lactic dehydrogenase levels in peritoneal blood and glutamic-oxalacetic transaminase levels in peritoneal and peripheral blood. A multiplicity of abdominal organ injury results in elevation of lactic dehydrogenase and glutamic-oxalacetic transaminase levels in peritoneal blood. The occurrence of isolated small intestinal injury and small intestinal injury combined with other organ injury produces a significant elevation of glutamic-oxalacetic transaminase, lactic dehydrogenase and alkaline phosphatase levels in peritoneal blood. The alkaline phosphatase elevation in peritoneal blood is associated with normal mean values in peripheral blood; therefore, combined alkaline phosphatase in peritoneal and peripheral blood has potential for use in the identification of small intestinal injury in patients with hemoperitoneum of traumatic origin.
采用自动化实验室方法，通过分析腹腔血液中的酶含量，对70例钝性和穿透性腹部创伤合并腹腔积血的患者进行了评估。评估腹腔血液中的酶水平，并与外周血中的同期水平进行比较，以确定与器官相关的腹腔血液和外周血液中的酶差异。本研究结果表明，单纯性肝损伤与腹腔血液中乳酸脱氢酶水平以及腹腔和外周血液中谷草转氨酶水平的显著升高有关。多种腹部器官损伤会导致腹腔血液中乳酸脱氢酶和谷草转氨酶水平升高。单纯性小肠损伤以及小肠损伤合并其他器官损伤会使腹腔血液中谷草转氨酶、乳酸脱氢酶和碱性磷酸酶水平显著升高。腹腔血液中碱性磷酸酶升高与外周血中的平均值正常相关；因此，腹腔和外周血液中的碱性磷酸酶联合检测有可能用于识别创伤性腹腔积血患者的小肠损伤。
