Kuscu Naci K, Koyuncu Faik M
Department of Obstetrics and Gynecology, Celal Bayar University, School of Medicine, Manisa, Turkey.
Medscape Womens Health. 2002 Sep-Oct;7(5):3.
Insulin plays a major role in polycystic ovary syndrome (PCOS). Insulin resistance and resultant hyperinsulinemia stimulate both the ovary and adrenal to produce androgens. Oral antidiabetic agents have been used to alleviate the symptoms and to induce ovulation in women with PCOS. This review focuses on the relation between insulin and PCOS and discusses the use of oral antidiabetic agents.
胰岛素在多囊卵巢综合征（PCOS）中起主要作用。胰岛素抵抗及由此产生的高胰岛素血症会刺激卵巢和肾上腺产生雄激素。口服抗糖尿病药物已被用于缓解多囊卵巢综合征女性的症状并诱导排卵。本综述重点关注胰岛素与多囊卵巢综合征之间的关系，并讨论口服抗糖尿病药物的使用。
