Obstet Gynecol. 2002 Dec;100(6):1413-6. doi: 10.1016/s0029-7844(02)02630-3.
The purpose of this Committee Opinion is to define the role of the generalist obstetrician-gynecologist in the early detection of ovarian cancer. Currently, it appears that the best way to detect early ovarian cancer is for both the patient and her clinician to have a high index of suspicion of the diagnosis in the symptomatic woman. In evaluating symptoms, physicians should perform a physical examination, including a pelvic examination. In premenopausal women with symptoms, a CA 125 measurement has not been shown to be useful in most circumstances. In postmenopausal women with a pelvic mass, a CA 125 measurement may be helpful in predicting a higher likelihood of a malignant tumor than a benign tumor, which may be useful in making consultation or referral decisions or both. A woman with a suspicious or persistent complex adnexal mass requires surgical evaluation by a physician trained to appropriately stage and debulk ovarian cancer. Data suggest that currently available screening tests do not appear to be beneficial for screening low-risk, asymptomatic women. An annual gynecologic examination with an annual pelvic examination is recommended for preventive health care.
本委员会意见的目的是明确普通妇产科医生在卵巢癌早期检测中的作用。目前，对于有症状的女性，检测早期卵巢癌的最佳方法似乎是患者及其临床医生都对该诊断保持高度怀疑指数。在评估症状时，医生应进行体格检查，包括盆腔检查。对于有症状的绝经前女性，在大多数情况下，CA 125检测并无用处。对于有盆腔肿块的绝经后女性，CA 125检测可能有助于预测恶性肿瘤的可能性高于良性肿瘤，这在做出会诊或转诊决定或两者兼有时可能有用。有可疑或持续性复杂附件包块的女性需要由接受过适当分期和减瘤手术培训的医生进行手术评估。数据表明，目前可用的筛查试验对低风险、无症状女性进行筛查似乎并无益处。建议每年进行妇科检查和盆腔检查以进行预防性医疗保健。
