Moody Karen, Charlson Mary E, Finlay Jonathan
Hospital and Medical Center, New York University, New York, NY, USA.
J Pediatr Hematol Oncol. 2002 Dec;24(9):717-21. doi: 10.1097/00043426-200212000-00007.
Despite improved survival of children with cancer, opportunistic infections remain a significant cause of morbidity and mortality in this population. Several interventions have been tried to decrease the incidence of infection by reducing patients' exposure to bacteria during neutropenia. The neutropenic diet is one such intervention that was intended to limit the introduction of bacteria into the host's gastrointestinal tract. The only studies evaluating this diet have used this strategy in combination with multiple other interventions, and the independent effect of this diet remains unknown. More research about the neutropenic diet is needed to establish its effectiveness in clinical practice.
尽管癌症患儿的生存率有所提高,但机会性感染仍是该人群发病和死亡的重要原因。人们已经尝试了多种干预措施,通过减少患者在中性粒细胞减少期间接触细菌的机会来降低感染发生率。中性粒细胞减少饮食就是这样一种干预措施,旨在限制细菌进入宿主胃肠道。仅有的评估这种饮食的研究都是将该策略与多种其他干预措施结合使用,这种饮食的独立效果仍然未知。需要更多关于中性粒细胞减少饮食的研究来确定其在临床实践中的有效性。