Universidade Federal de Minas Gerais, Hospital das Clínicas, Belo Horizonte, MG, Brazil.
Universidade Federal de Ouro Preto, Ouro Preto, MG, Brazil.
J Pediatr (Rio J). 2024 Mar-Apr;100(2):132-142. doi: 10.1016/j.jped.2023.07.009. Epub 2023 Oct 6.
to carry out a scoping review with the purpose of mapping the scientific evidence on the use of the neutropenic diet in neutropenic pediatric cancer patients.
The scoping review protocol was prepared in accordance with the PRISMA-ScR and the checklist before the literature search was performed. Articles on nutritional management in adults or on the treatment of other diseases, and articles that were not in Portuguese or English and published before the year 2000, were excluded. Data were extracted based on the Cochrane Consumer and Communication Review Group form.
Three hundred and forty scientific articles were identified, with the final sample of this review consisting of nine studies. Although the neutropenic diet has been part of the nutritional management of pediatric cancer patients for more than 20 years, there is still great variation in the criteria for indicating use and starting and discontinuing it, as well as in the nutritional composition of the diet. Furthermore, there is no consensus on the impact of using a neutropenic diet on different clinical and nutritional outcomes.
In the absence of guidelines that standardize the use of a neutropenic diet in pediatric patients with neutropenia, there are heterogeneous approaches reported in the literature, even within the same institution. The available literature presents an absence of evidence on the use, viability, and effectiveness of the neutropenic diet in oncological children with neutropenia. More studies are needed to identify the real impact of the neutropenic diet on clinical and nutritional outcomes.
开展范围综述,以绘制中性粒细胞减少症儿科癌症患者使用中性粒细胞减少症饮食的科学证据图谱。
根据 PRISMA-ScR 和文献检索前的清单,制定了范围综述方案。排除了关于成人营养管理或治疗其他疾病的文章,以及非葡萄牙语或英语的文章和 2000 年前发表的文章。根据 Cochrane 消费者和传播评论小组的表格提取数据。
共确定了 340 篇科学文章,本综述的最终样本由 9 项研究组成。尽管中性粒细胞减少症饮食已经成为儿科癌症患者营养管理的一部分超过 20 年,但在指示使用和开始及停止使用的标准以及饮食的营养成分方面仍存在很大差异。此外,对于使用中性粒细胞减少症饮食对不同临床和营养结果的影响,也没有共识。
由于缺乏标准化中性粒细胞减少症儿科患者使用中性粒细胞减少症饮食的指南,文献中报告了各种不同的方法,甚至在同一机构内也是如此。现有文献表明,中性粒细胞减少症饮食在中性粒细胞减少症肿瘤儿童中的使用、可行性和有效性缺乏证据。需要更多的研究来确定中性粒细胞减少症饮食对临床和营养结果的真正影响。