Robert A, Bonneville F, Miralbes S, Huart J Y, Cattin F, Quantin N, Bonneville J F
Service de Radiologie B, CHU J Minjoz, 25030 Besançon, Cedex, France.
J Radiol. 2002 Nov;83(11):1759-63.
To report the experience of using various Gadolinium chelates as contrast media in digital subtraction angiography in patients with relative or absolute contraindications for iodinated contrast agents.
and Methods. Forty-two arteriograms were performed in 39 consecutive patients using Gadolinium chelates (gadoteridol, gadodiamide, and gadopentetate dimeglumine). The vasculature of the brain, of the upper and lower limbs and the renal arteries were examined. Among these 39 patients, 17 were treated by various endovascular procedures.
In 40 examinations out of 42, the angiographic result was satisfactory, allowing either a diagnostic evaluation or an endovascular therapeutic procedure. Clinical tolerance was excellent. In one case of renal failure that was reported after angiography, the patient had received both iodine and gadolinum-based contrast agents.
Gadolinium appears to be an interesting alternative for arteriography in patients with absolute or relative contraindication to iodinated contrast agents, and also seems to demonstrate efficacy during endovascular therapeutic procedures.
报告在碘造影剂存在相对或绝对禁忌证的患者中,使用各种钆螯合物作为数字减影血管造影造影剂的经验。
材料与方法。连续39例患者使用钆螯合物(钆特醇、钆双胺和钆喷酸葡胺)进行了42次动脉造影。检查了脑、上肢和下肢以及肾动脉的血管系统。在这39例患者中,17例接受了各种血管内介入治疗。
42次检查中有40次血管造影结果令人满意,可用于诊断评估或血管内治疗。临床耐受性良好。在1例血管造影后报告的肾衰竭病例中,患者同时接受了碘造影剂和钆造影剂。
对于碘造影剂存在绝对或相对禁忌证的患者,钆似乎是动脉造影的一种有趣替代物,并且在血管内治疗过程中似乎也显示出疗效。