Kennedy H L, Das S K
Am Heart J. 1976 Feb;91(2):233-9. doi: 10.1016/s0002-8703(76)80579-0.
A case of PMIX with immunologic and viral studies obtained prior, during, and after a typical exacerbation are reported. Immunologic studies indicated the presence of humoral antiheart autoantibodies, and an increase in the number and proportion of lymphocytes containing surface IgG immunoglobulin during acute activity. Viral studies were negative. Previously reported immunologic and viral data, as well as etiology and pathogenesis of PMIS are discussed.
报告了一例在典型病情加重之前、期间及之后进行免疫和病毒学研究的混合性原发性免疫缺陷病(PMIX)病例。免疫研究表明存在体液抗心脏自身抗体,且在急性活动期含表面IgG免疫球蛋白的淋巴细胞数量和比例增加。病毒学研究为阴性。文中讨论了先前报道的免疫和病毒学数据以及混合性原发性免疫缺陷综合征(PMIS)的病因和发病机制。