Wenk R E, Lustagarten J A, Pappas N J, Levy R I, Jackson R
Am J Clin Pathol. 1976 Jan;65(1):49-57. doi: 10.1093/ajcp/65.1.49.
Current methods for determining serum chloride concentration vary in specificity. Laboratory detection of bromide in serum is usually dependent on spuriously high chloride values. In the absence of historical information, the chemical identification of bromide in serum may be the only diagnostic sign of bromism. Bromide may be found in as many as 1% of sera obtained from inpatients of a general hospital. Ion-selective electrodes and some thiocyanate methods for chloride analysis can be highly sensitive to bromide (interference). Chloride electrodes are also sensitive to iodide.
目前测定血清氯浓度的方法在特异性方面存在差异。血清中溴化物的实验室检测通常依赖于假性高氯值。在缺乏历史信息的情况下，血清中溴化物的化学鉴定可能是溴中毒的唯一诊断迹象。在综合医院住院患者的血清中，多达1%的样本可能会检测到溴化物。离子选择性电极和一些用于氯分析的硫氰酸盐方法对溴化物可能高度敏感（产生干扰）。氯电极对碘化物也敏感。
