Karnath Bernard M
University of Texas Medical Branch at Galveston, Galveston, Texas, USA.
Am Fam Physician. 2002 Nov 15;66(10):1889-96.
Heart disease is the leading cause of mortality in the United States. An important subset of heart disease is perioperative myocardial infarction, which affects approximately 50,000 persons each year. The American College of Cardiology (ACC) and American Heart Association (AHA) have coauthored a guideline on preoperative cardiac risk assessment, as has the American College of Physicians (ACP). The ACC/AHA guideline uses major, intermediate, and minor clinical predictors to stratify patients into different cardiac risk categories. Patients with poor functional status or those undergoing high-risk surgery require further risk stratification via cardiac stress testing. The ACP guideline also starts by screening patients for clinical variables that predict perioperative cardiac complications. However, the ACP did not feel there was enough evidence to support poor functional status as a significant predictor of increased risk. High-risk patients would sometimes merit preoperative cardiac catheterization by the ACC/AHA guideline, while the ACP version would reserve catheterization only for those who were candidates for cardiac revascularization independent of their noncardiac surgery. A recent development in prophylaxis of surgery-related cardiac complications is the use of beta blockers perioperatively for patients with cardiac risk factors.
心脏病是美国的主要死因。围手术期心肌梗死是心脏病的一个重要子集,每年影响约5万人。美国心脏病学会(ACC)和美国心脏协会(AHA)共同撰写了一份关于术前心脏风险评估的指南,美国医师学会(ACP)也发布了一份。ACC/AHA指南使用主要、中级和次要临床预测指标将患者分为不同的心脏风险类别。功能状态不佳的患者或接受高风险手术的患者需要通过心脏负荷试验进行进一步的风险分层。ACP指南也从筛查预测围手术期心脏并发症的临床变量开始。然而,ACP认为没有足够的证据支持功能状态不佳是风险增加的重要预测指标。根据ACC/AHA指南,高风险患者有时需要术前进行心脏导管插入术,而ACP版本则仅将导管插入术保留给那些独立于非心脏手术的心脏血运重建候选者。预防手术相关心脏并发症的最新进展是为有心脏风险因素的患者在围手术期使用β受体阻滞剂。