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1956年,在布拉干萨保利斯塔县的轻型天花疫情。两所学校不同人群单位的发病率,包括大多数患病学生。

Variola minor in Bragança Paulista county, 1956. Attack rates in various population units of the two schools including most students with the disease.

作者信息

Klauber M R, Angulo J J

出版信息

Am J Epidemiol. 1976 Jan;103(1):112-25. doi: 10.1093/oxfordjournals.aje.a112199.

Abstract

Overall attack rates were different for the two schools but were the same when only classes with cases were considered. Of the 49 classes (from both schools) with susceptible students, 29 had cases. In these, the attack rate among susceptibles ranged from 4-69%. The differences between the class rates were highly statistically significant. In the José Guilherme School, 17 out of 21 classes containing susceptibles had cases as compared with 12 out of 28 classes in the Jorge Tibiriçá School. Attack rates differed little between schools for either the early or late shift classes, but the attack rate for early shift classes in both schools together (39%) significantly exceeded that for the late shifts (16%). Within-shift attack rate differences were highly significant for the first-shift classes but not significant for classes in the other shifts. Attack rates differed significantly by classroom population (group of students using a classroom including all shifts), mainly because of heterogeneous rates in one school. Attack rates by desk column did not differ significantly even when comparing the column seating the earliest, the latest or the "previous" case in the class with the remaining columns. Attack rates by desk row also did not differ significantly. There was no important progressive association between attack rates and size of "unit of susceptibles" (group combining columns and rows), but there was a significant difference for unit size. Attack rates were not influenced by cluster seating of susceptibles.

摘要

两所学校的总体发病率有所不同,但仅考虑有病例的班级时发病率相同。在49个(来自两所学校)有易感学生的班级中,有29个班级出现了病例。在这些班级中,易感人群的发病率在4%至69%之间。班级发病率之间的差异具有高度统计学意义。在若泽·吉列尔梅学校,21个有易感学生的班级中有17个出现了病例,而在豪尔赫·蒂比里卡学校,28个班级中有12个出现了病例。两所学校早班或晚班课程的发病率差异不大,但两所学校早班课程的总发病率(39%)显著高于晚班(16%)。早班课程内的发病率差异非常显著,而其他班次课程的发病率差异不显著。发病率因教室人数(使用教室的包括所有班次的学生群体)而异,主要是因为一所学校的发病率存在异质性。即使将班级中最早、最晚或“前一个”病例所在列与其余列进行比较,按课桌列计算的发病率也没有显著差异。按课桌行计算的发病率也没有显著差异。发病率与“易感单位”(将列和行组合在一起的群体)的大小之间没有重要的递进关联,但单位大小存在显著差异。易感人群的集群座位安排对发病率没有影响。

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