Magos Adam
Minimally Invasive Therapy Unit and Endoscopy Training Centre, University Department of Obstetrics and Gynaecology, Royal Free Hospital, Pond Street, Hampstead, London NW3 2QG, UK.
Reprod Biomed Online. 2002;4 Suppl 3:46-51. doi: 10.1016/s1472-6483(12)60116-3.
Although Asherman's syndrome (the presence of adhesions inside the cervical canal or uterine cavity) is relatively uncommon in the general population, it can be the cause of menstrual irregularity and subfertility in high risk women. The diagnosis is usually confirmed by hysterosalpinography, and more recently by hysteroscopy. Hysteroscopy has also become accepted as the optimum route of surgery, the aims being to restore the size and shape of the uterine cavity, normal endometrial function and fertility. Treatment can range from simple cervical dilatation in the case of cervical stenosis but an intact uterine cavity, to extensive adhesiolysis of dense intrauterine adhesions using scissors or electro- or laser energy. Patients in whom the uterine fundus is completely obscured, and those with a greatly narrowed, fibrotic cavity present the greatest therapeutic challenge. Several techniques have described for these difficult cases, but outcome is far worse than in patients with mild, endometrial-type adhesions. Non-hysteroscopic techniques area also beginning to be developed, but whether they will replace the current 'gold' standard of hysteroscopy remains to be seen.
尽管阿谢曼综合征(宫颈管或子宫腔内存在粘连)在普通人群中相对不常见,但它可能是高危女性月经不调和生育力低下的原因。诊断通常通过子宫输卵管造影术来确认,最近也通过宫腔镜检查来确认。宫腔镜检查也已被公认为最佳的手术途径,其目的是恢复子宫腔的大小和形状、正常的子宫内膜功能和生育能力。治疗方法从宫颈狭窄但子宫腔完整的情况下进行简单的宫颈扩张,到使用剪刀、电或激光能量对致密的宫腔粘连进行广泛的粘连松解。子宫底完全被遮挡的患者以及宫腔严重狭窄、纤维化的患者面临着最大的治疗挑战。针对这些困难病例已经描述了几种技术,但结果远比轻度子宫内膜型粘连患者差。非宫腔镜技术也开始得到发展,但它们是否会取代当前宫腔镜检查的“金标准”还有待观察。