Bender Rukiye Ada, Özcan Canan, Akar Bertan, Çalışkan Eray
Biruni University School of Medicine, Department of Obstetrics and Gynecology, İstanbul, Turkey.
Medicana International Hospital, Clinic of Obstetrics and Gynecology, İstanbul, Turkey.
Turk J Obstet Gynecol. 2022 Sep 23;19(3):195-200. doi: 10.4274/tjod.galenos.2022.69705.
Intrauterine adhesion (IUA) is the formation of band-shaped fibrotic tissues in the endometrial cavity due to uterine procedures. Most adhesions remain asymptomatic and do not affect fertility or pregnancy conditions. However, they may lead to infertility and pregnancy complications in some women. This study aimed to determine which localization and type of IUA may lead to infertility.
Seventy-six women with IUA were retrospectively scanned. Thirty-nine women with IUA with uterine factor-related infertility were included in the infertility group. Thirty-seven pregnant women, who had adhesions in the second-trimester ultrasonography and who had a live birth via cesarean section at term, were included in the pregnancy group. The localization of adhesions was determined as the fundus, corpus, isthmus, and cornu. Concerning the type of adhesion, the adhesions were classified as dense- and film-type adhesions.
The infertility group was compared with the pregnancy group according to the type and localization of the adhesions. Fundal adhesions were significantly higher in the infertility group compared to the pregnancy group (p<0.05). The isthmic adhesions, however, were more common in the pregnancy group than in the infertility group (p<0.05). Dense-type adhesions were more common in the infertility group than in the pregnancy group (p<0.05).
According to the localization and types of adhesions, fundal and dense-type adhesions are among the features of uterine factor-related infertility. However, isthmus-located and film-type adhesions may not cause infertility.
宫腔粘连(IUA)是由于子宫手术导致子宫内膜腔内形成带状纤维化组织。大多数粘连无症状,不影响生育能力或妊娠情况。然而,在一些女性中,它们可能导致不孕和妊娠并发症。本研究旨在确定哪种IUA的定位和类型可能导致不孕。
对76例IUA患者进行回顾性扫描。不孕组纳入39例因子宫因素相关不孕的IUA患者。妊娠组纳入37例在孕中期超声检查时发现粘连且足月剖宫产分娩活婴的孕妇。粘连的定位确定为宫底、宫体、峡部和宫角。关于粘连类型,粘连分为致密型和薄膜型粘连。
根据粘连的类型和定位,将不孕组与妊娠组进行比较。与妊娠组相比,不孕组宫底粘连明显更高(p<0.05)。然而,峡部粘连在妊娠组比不孕组更常见(p<0.05)。致密型粘连在不孕组比妊娠组更常见(p<0.05)。
根据粘连的定位和类型,宫底和致密型粘连是子宫因素相关不孕的特征之一。然而,峡部定位的和薄膜型粘连可能不会导致不孕。