β-淀粉样蛋白：大脑的（生命）保护者。 - Suppr

Suppr

超能文献

Amyloid-beta: a (life) preserver for the brain.

作者信息

Obrenovich Mark E, Joseph James A, Atwood Craig S, Perry George, Smith Mark A

机构信息

Institute of Pathology, Case Western Reserve University, 2085 Adelbert Road, Cleveland, OH 44106, USA.

出版信息

Neurobiol Aging. 2002 Nov-Dec;23(6):1097-9. doi: 10.1016/s0197-4580(02)00038-6.

DOI:10.1016/s0197-4580(02)00038-6

PMID:12470809

Abstract

摘要

相似文献

Amyloid-beta: a (life) preserver for the brain.

Neurobiol Aging. 2002 Nov-Dec;23(6):1097-9. doi: 10.1016/s0197-4580(02)00038-6.

Testing times for the "amyloid cascade hypothesis".

Neurobiol Aging. 2002 Nov-Dec;23(6):1073-4. doi: 10.1016/s0197-4580(02)00042-8.

Bioflocculant hypothesis: a partial endorsement.

Neurobiol Aging. 2002 Nov-Dec;23(6):1075. doi: 10.1016/s0197-4580(02)00041-6.

Evolution and the scientific method.

Neurobiol Aging. 2002 Nov-Dec;23(6):1093-5. doi: 10.1016/s0197-4580(02)00039-8.

Is amyloid beta-peptide neurotoxic or neuroprotective and what is its role in the binding of metal ions?

Neurobiol Aging. 2002 Nov-Dec;23(6):1089-92. doi: 10.1016/s0197-4580(02)00037-4.

Abeta conformational change is central to Alzheimer's disease.

Neurobiol Aging. 2002 Nov-Dec;23(6):1085-8. doi: 10.1016/s0197-4580(02)00040-4.

Abeta as a bioflocculant: implications for the amyloid hypothesis of Alzheimer's disease.

Neurobiol Aging. 2002 Nov-Dec;23(6):1051-72. doi: 10.1016/s0197-4580(01)00342-6.

The amyloid hypothesis: let sleeping dogmas lie?

Neurobiol Aging. 2002 Nov-Dec;23(6):1101-5. doi: 10.1016/s0197-4580(02)00050-7.

Alzheimer's disease and Alzheimer's dementia: distinct but overlapping entities.

Neurobiol Aging. 2002 Nov-Dec;23(6):1077-84. doi: 10.1016/s0197-4580(02)00036-2.

Cat and mouse.

Neuron. 2006 Sep 21;51(6):671-2. doi: 10.1016/j.neuron.2006.09.005.

引用本文的文献

The Role of the Microbiota-Gut-Brain Axis and Antibiotics in ALS and Neurodegenerative Diseases.

Microorganisms. 2020 May 23;8(5):784. doi: 10.3390/microorganisms8050784.

Lipopolysaccharide endotoxemia induces amyloid-β and p-tau formation in the rat brain.

Am J Nucl Med Mol Imaging. 2018 Apr 25;8(2):86-99. eCollection 2018.

Phosphoinositides: Two-Path Signaling in Neuronal Response to Oligomeric Amyloid β Peptide.

Mol Neurobiol. 2017 Jul;54(5):3236-3252. doi: 10.1007/s12035-016-9885-3. Epub 2016 Apr 14.

Moving beyond anti-amyloid therapy for the prevention and treatment of Alzheimer's disease.

BMC Neurol. 2014 Sep 2;14:169. doi: 10.1186/s12883-014-0169-0.

Amyloid Beta and tau proteins as therapeutic targets for Alzheimer's disease treatment: rethinking the current strategy.

Int J Alzheimers Dis. 2012;2012:630182. doi: 10.1155/2012/630182. Epub 2012 Mar 8.

The biochemical aftermath of anti-amyloid immunotherapy.

Mol Neurodegener. 2010 Oct 7;5:39. doi: 10.1186/1750-1326-5-39.

The effects of cholesterol on learning and memory.

Neurosci Biobehav Rev. 2010 Jul;34(8):1366-79. doi: 10.1016/j.neubiorev.2010.04.010. Epub 2010 May 12.

The GRK2 Overexpression Is a Primary Hallmark of Mitochondrial Lesions during Early Alzheimer Disease.

Cardiovasc Psychiatry Neurol. 2009;2009:327360. doi: 10.1155/2009/327360. Epub 2010 Mar 3.

Bioluminescence imaging reveals inhibition of tumor cell proliferation by Alzheimer's amyloid beta protein.

Cancer Cell Int. 2009 Jun 1;9:15. doi: 10.1186/1475-2867-9-15.

Insights into cerebrovascular complications and Alzheimer disease through the selective loss of GRK2 regulation.

J Cell Mol Med. 2009 May;13(5):853-65. doi: 10.1111/j.1582-4934.2008.00512.x. Epub 2008 Oct 6.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

相似文献

Amyloid-beta: a (life) preserver for the brain.

Neurobiol Aging. 2002 Nov-Dec;23(6):1097-9. doi: 10.1016/s0197-4580(02)00038-6.

Testing times for the "amyloid cascade hypothesis".

Neurobiol Aging. 2002 Nov-Dec;23(6):1073-4. doi: 10.1016/s0197-4580(02)00042-8.

Bioflocculant hypothesis: a partial endorsement.

Neurobiol Aging. 2002 Nov-Dec;23(6):1075. doi: 10.1016/s0197-4580(02)00041-6.

Evolution and the scientific method.

Neurobiol Aging. 2002 Nov-Dec;23(6):1093-5. doi: 10.1016/s0197-4580(02)00039-8.

Is amyloid beta-peptide neurotoxic or neuroprotective and what is its role in the binding of metal ions?

Neurobiol Aging. 2002 Nov-Dec;23(6):1089-92. doi: 10.1016/s0197-4580(02)00037-4.

Abeta conformational change is central to Alzheimer's disease.

Neurobiol Aging. 2002 Nov-Dec;23(6):1085-8. doi: 10.1016/s0197-4580(02)00040-4.

Abeta as a bioflocculant: implications for the amyloid hypothesis of Alzheimer's disease.

Neurobiol Aging. 2002 Nov-Dec;23(6):1051-72. doi: 10.1016/s0197-4580(01)00342-6.

The amyloid hypothesis: let sleeping dogmas lie?

Neurobiol Aging. 2002 Nov-Dec;23(6):1101-5. doi: 10.1016/s0197-4580(02)00050-7.

Alzheimer's disease and Alzheimer's dementia: distinct but overlapping entities.

Neurobiol Aging. 2002 Nov-Dec;23(6):1077-84. doi: 10.1016/s0197-4580(02)00036-2.

Cat and mouse.

Neuron. 2006 Sep 21;51(6):671-2. doi: 10.1016/j.neuron.2006.09.005.

引用本文的文献

The Role of the Microbiota-Gut-Brain Axis and Antibiotics in ALS and Neurodegenerative Diseases.

Microorganisms. 2020 May 23;8(5):784. doi: 10.3390/microorganisms8050784.

Lipopolysaccharide endotoxemia induces amyloid-β and p-tau formation in the rat brain.

Am J Nucl Med Mol Imaging. 2018 Apr 25;8(2):86-99. eCollection 2018.

Phosphoinositides: Two-Path Signaling in Neuronal Response to Oligomeric Amyloid β Peptide.

Mol Neurobiol. 2017 Jul;54(5):3236-3252. doi: 10.1007/s12035-016-9885-3. Epub 2016 Apr 14.

Moving beyond anti-amyloid therapy for the prevention and treatment of Alzheimer's disease.

BMC Neurol. 2014 Sep 2;14:169. doi: 10.1186/s12883-014-0169-0.

Amyloid Beta and tau proteins as therapeutic targets for Alzheimer's disease treatment: rethinking the current strategy.

Int J Alzheimers Dis. 2012;2012:630182. doi: 10.1155/2012/630182. Epub 2012 Mar 8.

The biochemical aftermath of anti-amyloid immunotherapy.

Mol Neurodegener. 2010 Oct 7;5:39. doi: 10.1186/1750-1326-5-39.

The effects of cholesterol on learning and memory.

Neurosci Biobehav Rev. 2010 Jul;34(8):1366-79. doi: 10.1016/j.neubiorev.2010.04.010. Epub 2010 May 12.

The GRK2 Overexpression Is a Primary Hallmark of Mitochondrial Lesions during Early Alzheimer Disease.

Cardiovasc Psychiatry Neurol. 2009;2009:327360. doi: 10.1155/2009/327360. Epub 2010 Mar 3.

Bioluminescence imaging reveals inhibition of tumor cell proliferation by Alzheimer's amyloid beta protein.

Cancer Cell Int. 2009 Jun 1;9:15. doi: 10.1186/1475-2867-9-15.

Insights into cerebrovascular complications and Alzheimer disease through the selective loss of GRK2 regulation.

J Cell Mol Med. 2009 May;13(5):853-65. doi: 10.1111/j.1582-4934.2008.00512.x. Epub 2008 Oct 6.