Timoney J F
Am J Vet Res. 1976 Jan;37(1):5-8.
Concentrations of hemolytic complement and of 3rd component of complement were determined in serums and in synovia of normal and arthritic joints in swine affected with arthritis experimentally produced by the inoculation of Erysipelothrix rhusiopathiae. Mean concentrations of complement in arthritic joints were increased from 24.7 to 37.5 50% hemolytic units of complement per milliliter. Third component of complement, expressed as a percentage of the serum concentration, was increased from a mean of 16.9 (normal joint synovia) to a mean of 27.1 (arthritic joint synovia). Also, fast-migrating conversion products of 3rd component of complement were not detected in synovia from arthritic joints. These results are interpreted as indicating a relatively less important role for immune complexes in the pathogenesis of erysipelothrix arthritis than is described for rheumatoid arthritis in persons.
在通过接种猪丹毒杆菌实验性诱发关节炎的猪的血清和正常及关节炎关节的滑液中，测定了溶血补体和补体第三成分的浓度。关节炎关节中补体的平均浓度从每毫升24.7个50%溶血单位增加到37.5个。补体第三成分以血清浓度的百分比表示，从正常关节滑液的平均16.9%增加到关节炎关节滑液的平均27.1%。此外，在关节炎关节的滑液中未检测到补体第三成分的快速迁移转化产物。这些结果被解释为表明免疫复合物在猪丹毒杆菌关节炎发病机制中的作用相对不如人类类风湿性关节炎中所描述的那样重要。
