Andersson A, Bergdahl L, Boquist L
Ann Surg. 1976 Jan;183(1):53-7. doi: 10.1097/00000658-197601000-00011.
Primary adenocarcinoma of the appendix is rare and less than 200 cases are on record. The present material consisted of 20 cases collected from different hospitals. The cases are described in respect of sex and age-distribution, symptoms, treatment and prognosis. Of 7 patients with malignant mucocele, 6 subjected to appendectomy only, were still alive 5 years after the operation. Of 12 patients with colonic type of adenocarcinoma, 3 had been treated with appendectomy only. Of these, 2 were still alive 5 years after the operation. The remaining 9 patients had undergone right hemicolectomy. Only one of them was alive 5 years after the operation. A compilation of a further 39 cases garnered from the literature, however, showed that 60% had survived at least 5 years after right hemicolectomy, compared with 46% after appendectomy alone. Appendectomy alone is probably a sufficiently radical operation for malignant mucocele provided the tumor has not grown through the submucosa and that it is confined to the tip of the appendix. Right hemicolectomy is indicated for the colonic type of adenocarcinoma.
阑尾原发性腺癌罕见,有记录的病例不足200例。本研究资料包括从不同医院收集的20例病例。对这些病例的性别、年龄分布、症状、治疗及预后进行了描述。7例黏液性囊腺癌患者中,6例仅接受了阑尾切除术,术后5年仍存活。12例结肠型腺癌患者中,3例仅接受了阑尾切除术。其中,2例术后5年仍存活。其余9例患者接受了右半结肠切除术。术后5年只有1例存活。然而,从文献中收集的另外39例病例显示,右半结肠切除术后至少5年生存率为60%,而单纯阑尾切除术后为46%。如果肿瘤未穿透黏膜下层且局限于阑尾尖端,单纯阑尾切除术可能是治疗黏液性囊腺癌的足够根治性手术。结肠型腺癌则需行右半结肠切除术。