Vodusek David B
Division of Neurology, University Medical Centre, Ljubljana, Slovenia.
Scand J Urol Nephrol Suppl. 2002(210):51-4.
Electrophysiological techniques applied either for diagnostic or therapeutic reasons have contributed to elucidation of the neurocontrol of micturition. But the ability of electrophysiological diagnostic tests to reveal neurogenic involvement in patients suffering from lower urinary tract dysfunction is limited, and has been overestimated. Furthermore, the correlation between a proven neurogenic deficit and the consecutive dysfunction is complex. The electrophysiological tests, however, may also be applied for testing the central nervous system integrative function, such as in testing reflex thresholds, excitability levels of motor nuclei, etc. The use of electrical stimulation for therapeutic purposes has instigated much physiological research. Insights related to micturition neurocontrol, as for instance that afferent inputs from lumbosacral and vesical sensory fibres modulate the micturition threshold, are being therapeutically exploited. It is expected that further use of electrophysiological techniques, being complementary to functional neuroimaging, will clarify particularly the temporal aspects of neurocontrol mechanisms involved in micturition.
出于诊断或治疗目的应用的电生理技术，有助于阐明排尿的神经控制机制。但电生理诊断测试揭示下尿路功能障碍患者神经源性受累情况的能力有限，且被高估了。此外，已证实的神经源性缺陷与随之而来的功能障碍之间的相关性很复杂。然而，电生理测试也可用于测试中枢神经系统的整合功能，比如测试反射阈值、运动核的兴奋性水平等。将电刺激用于治疗目的引发了大量生理学研究。与排尿神经控制相关的见解，例如来自腰骶部和膀胱感觉纤维的传入输入调节排尿阈值，正被用于治疗。预计电生理技术作为功能神经成像的补充，进一步应用将特别阐明排尿所涉及的神经控制机制的时间方面。
