Green Francis H Y
University of Calgary, Calgary, AB, Canada.
Chest. 2002 Dec;122(6 Suppl):334S-339S. doi: 10.1378/chest.122.6_suppl.334s.
Pulmonary fibrosis is a component of over 200 interstitial lung diseases. Some have known etiologies, however, for many diseases, the etiology remains unknown or obscure. This brief review examines the prevalence and classification of these diseases, the approach to be taken for the investigation of a patient suspected of having pulmonary fibrosis, the indications for the performance of lung biopsy, and current thoughts concerning the pathogenesis of the idiopathic forms of fibrotic lung disease. A brief review of established and emerging therapeutic strategies is included.
肺纤维化是200多种间质性肺疾病的一个组成部分。有些疾病有已知的病因,然而,对于许多疾病来说,病因仍然不明或不清楚。本简要综述探讨了这些疾病的患病率和分类、对疑似患有肺纤维化患者的调查方法、肺活检的指征以及关于特发性纤维化肺病发病机制的当前观点。还包括对既定和新兴治疗策略的简要综述。