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细菌性心内膜炎与功能性二尖瓣狭窄:两例报告及文献简要综述

Bacterial endocarditis and functional mitral stenosis: a report of two cases and brief literature review.

作者信息

Tiong Irving Y, Novaro Gian M, Jefferson Brian, Monson Michael, Smedira Nicholas, Penn Marc S

机构信息

Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

出版信息

Chest. 2002 Dec;122(6):2259-62. doi: 10.1378/chest.122.6.2259.

Abstract

Mitral valve endocarditis typically results in mitral regurgitation. However, endocarditis leading to functional mitral stenosis is uncommon and, when present, fungal organisms are typically implicated. Thus, obstructive-type bacterial endocarditis due to large vegetations blocking the mitral valve orifice is a rare occurrence, with approximately 20 reported cases in the literature. We report on two patients with bacterial endocarditis and severe functional mitral stenosis requiring emergent surgery. Additionally, this is the first report of vancomycin-resistant enterococcus causing endocarditis and functional mitral stenosis. The discussion emphasizes the hemodynamic instability of these patients and need for early surgical intervention.

摘要

二尖瓣心内膜炎通常会导致二尖瓣反流。然而,导致功能性二尖瓣狭窄的心内膜炎并不常见,一旦出现,通常与真菌病原体有关。因此,由于巨大赘生物阻塞二尖瓣口而导致的梗阻型细菌性心内膜炎是一种罕见情况,文献中报道的病例约有20例。我们报告了两名患有细菌性心内膜炎和严重功能性二尖瓣狭窄且需要紧急手术的患者。此外,这是首例关于耐万古霉素肠球菌导致心内膜炎和功能性二尖瓣狭窄的报告。讨论强调了这些患者的血流动力学不稳定以及早期手术干预的必要性。

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