Hart Michael A, Shroff Gautam R
General Internal Medicine, Hennepin County Medical Center, 701 Park Avenue, Minneapolis, MN, 55415, USA.
Cardiology, Hennepin County Medical Center, 701 Park Avenue, Minneapolis, MN, 55415, USA.
J Med Case Rep. 2017 Feb 17;11(1):44. doi: 10.1186/s13256-017-1197-3.
Infective endocarditis rarely causes mitral valve stenosis. When present, it has the potential to cause severe hemodynamic decompensation and death. There are only 15 reported cases in the literature of mitral prosthetic valve bacterial endocarditis causing stenosis by obstruction. This case is even more unusual due to the mechanism by which functional mitral stenosis occurred.
We report a case of a 23-year-old white woman with a history of intravenous drug abuse who presented with acute heart failure. Transthoracic echocardiography failed to show valvular vegetation, but high clinical suspicion led to transesophageal imaging that demonstrated infiltrative prosthetic valve endocarditis causing severe mitral stenosis. Despite extensive efforts from a multidisciplinary team, she died as a result of her critical illness.
The discussion of this case highlights endocarditis physiology, the notable absence of stenosis in modified Duke criteria, and the utility of transesophageal echocardiography in clinching a diagnosis. It advances our knowledge of how endocarditis manifests, and serves as a valuable lesson for clinicians treating similar patients who present with stenosis but no regurgitation on transthoracic imaging, as a decision to forego a transesophageal echocardiography could cause this serious complication of endocarditis to be missed.
感染性心内膜炎很少导致二尖瓣狭窄。一旦出现,它有可能导致严重的血流动力学失代偿和死亡。文献中仅报道了15例人工二尖瓣细菌性心内膜炎因梗阻导致狭窄的病例。由于功能性二尖瓣狭窄发生的机制,该病例更为罕见。
我们报告一例23岁有静脉药物滥用史的白人女性,她因急性心力衰竭就诊。经胸超声心动图未显示瓣膜赘生物,但高度的临床怀疑促使进行经食管成像,结果显示为浸润性人工瓣膜心内膜炎导致严重二尖瓣狭窄。尽管多学科团队付出了巨大努力,但她最终因重病死亡。
对该病例的讨论突出了心内膜炎的生理机制、改良杜克标准中明显缺乏狭窄标准以及经食管超声心动图在确诊中的作用。它增进了我们对心内膜炎表现形式的认识,并为治疗类似患者的临床医生提供了宝贵的经验教训,这些患者在经胸成像中表现为狭窄但无反流,若决定不进行经食管超声心动图检查,可能会漏诊心内膜炎的这种严重并发症。