Fukada J, Morishita K, Kawaharada N, Muraki S, Satsu T, Kurimoto Y, Abe T
Department of Cardiothoracic Surgery, Sapporo Medical University, Sapporo, Japan.
Kyobu Geka. 2002 Dec;55(13):1087-93; discussion 1093-6.
One hundred eighty two patients with thoracic aortic aneurysms or dissections who required total arch replacement (TAR) were operated on with separated graft technique and selective cerebral perfusion (SCP) between 1991 and 2000. These patients were divided into 4 groups according to the pathology as follows: group 1; acute type A dissection, group 2; chronic type A dissection, group 3; distal arch aneurysm and group 4; proximal arch aneurysm. For SCP, both the innominate artery and the left common carotid artery were cannulated when the patient was cooled to a rectal temperature of 22 degrees C. Hospital mortalities were 27% in group 1, 14% in group 2, 19% in group 3, and 8% in group 4. Independent predictors of hospital mortality were shock, visceral, and leg ischemia in group 1, and circulatory arrest time of the lower half body to be more than 1 hour and cardiopulmonary bypass time to be more than 5 hours in group 3. Permanent neurological complication occurred in 3% in group 1 and 8% in group 3. Hospital mortality was affected by the type of aneurysms and dissections. It is necessary to give careful consideration to the indication of TAR with SCP, especially in acute type A dissection and distal arch aneurysm.
1991年至2000年间,182例需要进行全弓置换(TAR)的胸主动脉瘤或夹层患者采用了分离移植物技术和选择性脑灌注(SCP)进行手术。根据病理情况,这些患者被分为4组:第1组为急性A型夹层;第2组为慢性A型夹层;第3组为远端弓部动脉瘤;第4组为近端弓部动脉瘤。对于SCP,当患者体温降至直肠温度22℃时,同时对无名动脉和左颈总动脉进行插管。第1组的医院死亡率为27%,第2组为14%,第3组为19%,第4组为8%。第1组医院死亡的独立预测因素为休克、内脏和腿部缺血,第3组为下半身循环阻断时间超过1小时和体外循环时间超过5小时。第1组永久性神经并发症发生率为3%,第3组为8%。医院死亡率受动脉瘤和夹层类型的影响。对于采用SCP的TAR指征,尤其是急性A型夹层和远端弓部动脉瘤,有必要仔细考虑。