Division of Cardiothoracic Surgery, Department of Surgery, Oregon Health and Science University, Portland, Oregon, USA.
Division of Cardiothoracic Surgery, Department of Surgery, University of Colorado, Denver, Colorado, USA.
Heart Surg Forum. 2020 Mar 9;23(2):E107-E113. doi: 10.1532/hsf.2831.
Hybrid repair procedures of the aortic arch have been utilized to reduce surgical risks and apply this therapy to patients who would not traditionally be candidates for open surgical repair. We present a variation on the frozen elephant trunk technique to further reduce cardiopulmonary bypass and circulatory arrest duration.
After initiation of cardiopulmonary bypass and during systemic cooling, a wire is advanced from the femoral artery into the aortic arch. In the case of aortic dissection, intravascular ultrasound is used to confirm true lumen placement. Under circulatory arrest, the proximal aortic arch is resected and the wire externalized. Antegrade deployment of a stent graft is performed into the aortic arch and proximal descending aorta. The ascending aortic graft is sewn to the cut end of the aorta, incorporating the stent graft. The graft is cannulated and cardiopulmonary bypass reinitiated. The remainder of the arch replacement is performed during re-warming.
Twenty two patients underwent this novel hybrid arch replacement procedure for aortic pseudoaneurysm, aortic dissection, or aneurysm. In comparison to the frozen elephant trunk procedure, where a dacron graft is inserted into the descending aorta, and later fixed with an endograft, this technique allows for immediate distal fixation. In the case of aortic dissection, there is immediate expansion of the true lumen with distal seal, potentially obviating the need for additional procedures. Mean duration of follow up is 12 months (range 1 - 14 months). The mean duration of cardiopulmonary bypass was 109.32 ±3.14 minutes. The mean duration of circulatory arrest was 18.00 ±1.33 minutes at a mean temperature of 23.64 ±0.58 degrees Celsius. There were no mortalities, no permanent disabling strokes, and no renal failure (requiring dialysis).
This novel hybrid technique for aortic arch replacement is safe, significantly reduces cardiopulmonary bypass and circulatory arrest times, and is performed readily without need for fluoroscopy. In patients with thoracoabdominal aneurysms, the stent graft can be used as an elephant trunk for further thoracoabdominal aneurysm repair or branched thoracic endovascular aortic repair procedures.
主动脉弓的杂交修复术已被用于降低手术风险,并将该疗法应用于传统上不适合开放手术修复的患者。我们提出了一种改良的冷冻象鼻技术,以进一步减少体外循环和循环阻断时间。
在体外循环开始后和全身降温期间,将一根导丝从股动脉推进主动脉弓。在主动脉夹层的情况下,使用血管内超声确认真腔位置。在循环阻断期间,切除近端主动脉弓并将导丝引出。顺行置入支架移植物到主动脉弓和近端降主动脉。将升主动脉移植物缝合到主动脉的切断端,包括支架移植物。将移植物插管并重新开始体外循环。在复温过程中进行其余的弓部替换。
22 例患者因主动脉假性动脉瘤、主动脉夹层或动脉瘤而行这种新型杂交弓部替换术。与将涤纶移植物插入降主动脉,然后用血管内移植物固定的冷冻象鼻手术相比,该技术允许立即进行远端固定。在主动脉夹层的情况下,真腔立即扩张并在远端密封,可能避免需要额外的手术。平均随访时间为 12 个月(范围为 1-14 个月)。体外循环的平均时间为 109.32±3.14 分钟。循环阻断的平均时间为 18.00±1.33 分钟,平均温度为 23.64±0.58 摄氏度。无死亡,无永久性致残性中风,无肾功能衰竭(需要透析)。
这种新型主动脉弓部替换杂交技术安全,显著减少体外循环和循环阻断时间,无需透视即可顺利进行。在胸腹主动脉瘤患者中,支架移植物可用作象鼻,用于进一步的胸腹主动脉瘤修复或分支胸主动脉腔内修复术。