[从呼吸道感染患者中分离出的A组β溶血性链球菌的红霉素耐药性]

[Erythromycin resistance of group A beta-hemolytic streptococci isolated from patients with upper respiratory tract infections].

作者信息

Yazgi Halil, Ertek Mustafa, Aktaş A Esin

机构信息

10. Türk Klinik Mikrobiyoloji ve Infeksiyon Hastaliklari Kongresi'nde (15-19 Ekim 2001) sunulmuştur.

出版信息

Mikrobiyol Bul. 2002 Jan;36(1):11-4.

PMID:12476761

Abstract

The purpose of this study was to determine the erythromycin resistance of group A beta-hemolytic streptococci (GABHS) isolated from throat cultures. GABHS were isolated from 74 (10.4%) throat cultures of 710 patients with upper respiratory tract infections. Penicillin resistance was observed in none of the strains. Of these strains, 4 (5.4%) were found to be resistant to erythromycin. It was concluded that erythromycin resistance in GABHS, although high in some countries, was not a problem in our country at the moment. So, penicillin G and its alternative erythromycin and other macrolides are still reliable antibiotics for the treatment of GABHS infections.

摘要

本研究的目的是确定从咽喉培养物中分离出的A组β溶血性链球菌（GABHS）对红霉素的耐药性。从710例上呼吸道感染患者的74份（10.4%）咽喉培养物中分离出GABHS。所有菌株均未观察到对青霉素耐药。在这些菌株中，发现4株（5.4%）对红霉素耐药。得出的结论是，GABHS对红霉素的耐药性虽然在一些国家较高，但目前在我国不是一个问题。因此，青霉素G及其替代药物红霉素和其他大环内酯类药物仍是治疗GABHS感染的可靠抗生素。