Cengiz A T, Kiyan M, Ciftçioğlu N
Ankara Universitesi, Tip Fakültesi, Mikrobiyoloji Anabilim Dali, Başkani.
Mikrobiyol Bul. 1989 Apr;23(2):163-73.
In this study, we researched the susceptibility of group A Beta-hemolytic Streptococcus to antibiotics which are isolated from 218 Aydinlikevler primary blind boarding school students aged between 7-16 and a group of patient's throat and nose culture with acute and chronic upper respiratory tract infection. The susceptibility to 9 antibiotics of (100) group A Beta hemolytic Streptococcus which were isolated 52 from throat, 48 from nasal discharge were examined by the method of disc diffusion test after determination of the colony, hemolysis and staining characteristics also the sensibility to optochine and bacitracin (0.04 U) discs colonies. The antibiotic resistance ratio are observed as 24%. For Penicillin-G, 59% for Ampicillin, 17% for Amoxicillin, 31% for Methicillin, 22% for Cephalexin, 33% for Carbenicillin, 77% for Lincomycin, 60% for Trimethoprim/Sulphamethoxazole, 26% for Chloramphenicol. This finding shows that group A Beta hemolytic Streptococcus are getting being resistant to this 9 antibiotics. Also this results indicate that the treatment after antibiotic susceptibility test of group A Beta hemolytic Streptococcus is more effective.
在本研究中，我们对从218名年龄在7至16岁的艾丁利克勒初级寄宿学校学生以及一组患有急慢性上呼吸道感染的患者的咽喉和鼻腔培养物中分离出的A组β溶血性链球菌对抗生素的敏感性进行了研究。在确定菌落、溶血和染色特征后，通过纸片扩散试验方法检测了从咽喉分离出的52株和从鼻分泌物中分离出的48株共100株A组β溶血性链球菌对9种抗生素的敏感性，以及对奥普托欣和杆菌肽（0.04 U）纸片菌落的敏感性。观察到抗生素耐药率为24%。对青霉素G的耐药率为59%，氨苄西林为17%，阿莫西林为31%，甲氧西林为22%，头孢氨苄为33%，羧苄西林为77%，林可霉素为60%，甲氧苄啶/磺胺甲恶唑为26%，氯霉素为26%。这一发现表明A组β溶血性链球菌对这9种抗生素产生了耐药性。此外，这些结果表明对A组β溶血性链球菌进行抗生素敏感性试验后进行治疗更有效。
