Ergin Cagri, Ergin Seniz, Arikan Sevtap
Department of Microbiology, Medical Faculty, Pamukkale University, Denizli, Turkey.
Scand J Infect Dis. 2002;34(10):753-5. doi: 10.1080/00365540210147868.
Mal de Meleda is a rare autosomal recessive form of palmoplantar keratoderma characterized by hyperkeratosis of the palms and soles. The presence of yeast and dermatophytes was investigated in 29 mal de Meleda patients from Koprucay canyon, Turkey, a newer geographical focus, and was found in 62.0% and 20.7% of cases, respectively. Antifungal resistance of isolates was not detected.
梅勒达病是一种罕见的常染色体隐性遗传性掌跖角化病，其特征为手掌和足底过度角化。对来自土耳其科普鲁恰伊峡谷（一个新发现的地理病灶）的29例梅勒达病患者进行了酵母菌和皮肤癣菌检测，结果分别在62.0%和20.7%的病例中发现了这两种菌。未检测到分离株的抗真菌耐药性。
