Vikram Holenarasipur R, Bia Frank J
Department of Medicine, Section of Infectious Diseases, Hospital of St. Raphael, Yale University School of Medicine, New Haven, Connecticut 06511, USA.
Scand J Infect Dis. 2002;34(10):772-4. doi: 10.1080/00365540260348608.
Iron plays a crucial role in the energy metabolism of microorganisms. Humans have developed iron-withholding mechanisms as a form of non-specific immunity. We describe a patient with iron overload and severe Legionella pneumophila pneumonia. This report emphasizes the importance of early consideration of and appropriate therapy against Legionella for patients with iron overload who present with community-acquired pneumonia.
铁在微生物的能量代谢中起着至关重要的作用。人类已经发展出铁扣留机制作为一种非特异性免疫形式。我们描述了一名患有铁过载和严重嗜肺军团菌肺炎的患者。本报告强调了对于出现社区获得性肺炎的铁过载患者,早期考虑并针对军团菌进行适当治疗的重要性。