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重症嗜肺军团菌肺炎与无创通气:两例病例报告及文献简要回顾

Severe Legionella pneumophila pneumonia and non-invasive ventilation: presentation of two cases and brief review of the literature.

作者信息

Nicolini Antonello, Ferraioli Gianluca, Senarega Renata

机构信息

Respiratory Diseases Unit, General Hospital, via Terzi 43, Sestri Levante, Italy.

出版信息

Pneumonol Alergol Pol. 2013;81(4):399-403.

Abstract

Legionella pneumophila is an agent also well known to be frequently responsible for severe community acquired pneumonia. Recent studies regarding severe community-acquired pneumonia have shown that Legionella pneumophila is the second most common cause of admission to ICU, not far behind pneumococcal pneumonia. The mortality of severe Legionella pneumonia is high (30%). We report two cases of severe respiratory failure due to Legionella pneumophila type 1 treated with non-invasive ventilation in the Respiratory Intermediate Care Unit of a Department of Respiratory Medicine with good outcomes. Severe community-acquired pneumonia is the most common cause of ARDS, and it is the primary reason for Intensive Care Unit admission with invasive mechanical ventilation. Delay in ICU admission is probably associated with a poorer outcome. The use of non-invasive ventilation in severe community acquired pneumonia is controversial. However, after recent pandemics, the number of studies reporting good rates of success for NIV has increased. Both our patients were managed in a respiratory intermediate care unit, avoiding invasive ventilation and invasive monitoring, which lowered costs yet was equally effective in providing a good outcome when compared to intubation in the Intensive Care Unit.

摘要

嗜肺军团菌也是一种众所周知的常导致严重社区获得性肺炎的病原体。近期关于严重社区获得性肺炎的研究表明,嗜肺军团菌是重症监护病房(ICU)收治的第二大常见病因,仅次于肺炎球菌肺炎。严重军团菌肺炎的死亡率很高(30%)。我们报告了两例由1型嗜肺军团菌导致的严重呼吸衰竭病例,在一家呼吸内科的呼吸中级护理单元采用无创通气治疗,取得了良好效果。严重社区获得性肺炎是急性呼吸窘迫综合征(ARDS)最常见的病因,也是因有创机械通气而入住重症监护病房的主要原因。延迟入住ICU可能与较差的预后相关。在严重社区获得性肺炎中使用无创通气存在争议。然而,在近期的大流行之后,报告无创通气成功率较高的研究数量有所增加。我们的两名患者均在呼吸中级护理单元接受治疗,避免了有创通气和有创监测,这降低了成本,而且与在重症监护病房进行插管相比,在取得良好治疗效果方面同样有效。

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