一名非霍奇金淋巴瘤患者发生播散性皮肤海分枝杆菌感染。

Disseminated cutaneous Mycobacterium marinum infection in a patient with non-Hodgkin's lymphoma.

作者信息

Enzensberger R, Hunfeld K-P, Elshorst-Schmidt T, Böer A, Brade V

机构信息

Dept. of Medical Microbiology, Johann Wolfgang Goethe University of Frankfurt am Main, Paul-Ehrlich Str. 40, D-60596 Frankfurt am Main, Germany.

出版信息

Infection. 2002 Dec;30(6):393-5. doi: 10.1007/s15010-002-2063-8.

DOI:10.1007/s15010-002-2063-8

PMID:12478331

Abstract

A 60-year-old woman with non-Hodgkin's lymphoma was admitted to the hospital because of extensive subcutaneous abscesses developing on all limbs. The patient had an aquarium and kept tropical fish as pets. After repeated investigations, the diagnosis of Mycobacterium marinum was established from skin biopsy by PCR and culture. Long-term therapy with several drugs regimens had only a limited efficacy and was accompanied by severe adverse reactions. This report highlights the therapeutic problems posed by disseminated cutaneous M. marinum infection in the immunosuppressed host.

摘要

一名60岁的非霍奇金淋巴瘤女性患者因四肢出现广泛的皮下脓肿而入院。该患者有一个水族箱，并饲养热带鱼作为宠物。经过反复检查，通过聚合酶链反应（PCR）和培养从皮肤活检中确诊为海分枝杆菌感染。几种药物方案的长期治疗效果有限，且伴有严重不良反应。本报告强调了免疫抑制宿主中播散性皮肤海分枝杆菌感染所带来的治疗问题。