Dorronsoro I, Sarasqueta R, González A I, Gállego M
Servicio de Microbiología, Hospital de Navarra.
Enferm Infecc Microbiol Clin. 1997 Feb;15(2):82-4.
Human infection by Mycobacterium marinum is infrequent and is currently reported in association with the management of aquariums. The epidemiologic, clinical and microbiologic characteristics of three cases in our hospital are herein reported.
Three cases of cutaneous infection by M. marinum attended in our hospital from February 1993 to October 1994 are described.
The three patients were related with the management of aquariums. In two cases the clinical presentation was of sporotricoid cutaneous dissemination, while the third patient presented a localized cutaneous form. The lesions were localized in the upper right extremity in the three cases. The delay in diagnosis was important in two of the cases. Cure, or improvement, were achieved in three cases with' treatment; one with cotrimoxazol, another with first line tuberculostatic drugs and another did not receive treatment.
Human infection by M. marinum is currently described is association with the management of aquariums. The infection is usually cutaneous, alone or well disseminated, with invasion of deep tissue occasionally observed. The lesions are generally found on the upper extremities. Diagnostic delay is frequent. The most adequate treatment appears to be the combination of rifampicin plus etambutol or cotrimoxazol alone, with cases of spontaneous remission also being observed.
海分枝杆菌感染人类的情况并不常见,目前报道多与水族馆管理相关。本文报告我院3例患者的流行病学、临床及微生物学特征。
描述了我院1993年2月至1994年10月收治的3例海分枝杆菌皮肤感染病例。
3例患者均与水族馆管理有关。2例临床表现为皮肤孢子丝菌病样播散,第3例为局限性皮肤型。3例病变均位于右上臂。2例诊断延误情况较为严重。3例患者经治疗后均治愈或病情改善;1例使用复方新诺明,1例使用一线抗结核药物,另1例未接受治疗。
目前描述的人类海分枝杆菌感染与水族馆管理有关。感染通常为皮肤感染,可为单发或广泛播散,偶尔可见深部组织受累。病变一般位于上肢。诊断延误较为常见。最适当的治疗似乎是利福平加乙胺丁醇联合用药或单用复方新诺明,也有自发缓解的病例。