Endicott Phillip, Gilbert M Thomas P, Stringer Chris, Lalueza-Fox Carles, Willerslev Eske, Hansen Anders J, Cooper Alan
Henry Wellcome Ancient Biomolecules Centre, Department of Zoology, University of Oxford, Oxford, OX1 3PS England.
Am J Hum Genet. 2003 Jan;72(1):178-84. doi: 10.1086/345487. Epub 2002 Dec 11.
Mitochondrial sequences were retrieved from museum specimens of the enigmatic Andaman Islanders to analyze their evolutionary history. D-loop and protein-coding data reveal that phenotypic similarities with African pygmoid groups are convergent. Genetic and epigenetic data are interpreted as favoring the long-term isolation of the Andamanese, extensive population substructure, and/or two temporally distinct settlements. An early colonization featured populations bearing mtDNA lineage M2, and this lineage is hypothesized to represent the phylogenetic signal of an early southern movement of humans through Asia. The results demonstrate that Victorian anthropological collections can be used to study extinct, or seriously admixed populations, to provide new data about early human origins.
从神秘的安达曼岛民的博物馆标本中提取线粒体序列，以分析他们的进化历史。D环和蛋白质编码数据显示，与非洲俾格米人群体的表型相似性是趋同的。遗传和表观遗传数据被解释为支持安达曼人的长期隔离、广泛的种群亚结构和/或两个在时间上不同的定居点。早期的一次殖民活动中有携带线粒体DNA谱系M2的人群，据推测，这一谱系代表了人类早期从亚洲南部迁移的系统发育信号。结果表明，维多利亚时代的人类学藏品可用于研究灭绝的或严重混合的人群，从而提供有关早期人类起源的新数据。
