Suppr超能文献

[双腔起搏对80岁以上既往有阵发性房颤发作患者的安全性和有效性]

[Safety and effectiveness of dual chamber pacing in patients over 80 years of age with previous episodes of paroxysmal atrial fibrillation].

作者信息

Hrovatin Enzo, Zardo Fabio, Brieda Marco, Dametto Ermanno, Sparacino Lina, Antonini-Canterin Francesco, Burelli Claudio, Huang Guoqian, Nicolosi Gian Luigi

机构信息

U.O. di Cardiologia-ARC Dipartimento di Emergenza Azienda Ospedaliera S. Maria degli Angeli Via Montereale, 24 33170 Pordenone.

出版信息

Ital Heart J Suppl. 2002 Oct;3(10):1027-33.

Abstract

BACKGROUND

Dual chamber pacing (DDD) in the elderly is still a controversial issue because of its short life expectancy and the risk of atrial fibrillation. The aim of the study was 1) to evaluate the cumulative survival and the events capable of modifying it, 2) to evaluate the stability of sinus rhythm, and 3) to try to identify patients who are at a higher risk of developing permanent atrial fibrillation after DDD implantation. We evaluated clinical, electrophysiological and pacing parameters at the time of implantation.

METHODS

We examined retrospectively a group of 135 consecutive patients who were > 80 years old and who were treated with DDD in the last decade.

RESULTS

At the time of evaluation (mean 33.51 +/- 27.10 months, range 4-148 months) after DDD implantation, 72% of patients were still alive. Sinus rhythm was documented in 96 (71%) patients (group A). Thirty-nine (29%) patients (group B) developed atrial fibrillation after a mean period of 28.56 +/- 30.9 months (range 1-125 months). The right atrial endocavitary signal amplitude was lower in group B compared to that observed in group A (2.6 +/- 1.16 vs 3.27 +/- 1.91 mV). The pacing and sensing atrioventricular delay were not statistically different in both groups. The minimum heart rate was higher in patients who developed atrial fibrillation (64.53 +/- 7.7 vs 67.7 +/- 5.72 b/min respectively in group A and in group B, p = 0.02). Group B patients had a higher rate of atrial fibrillation pre-implantation episodes. The incidences of sick sinus disease and of atrioventricular nodal disease were similar in both groups.

CONCLUSIONS

In elderly patients the benefits of DDD are maintained for a long period of time before the development of atrial fibrillation. Episodes of atrial fibrillation prior to DDD, apart from sinus dysfunction alone, are predictive of the development of a permanent atrial fibrillation. Permanent atrial fibrillation does not seem to reduce life expectancy. A higher minimum heart rate does not seem to prevent atrial fibrillation. The capability of recording a right atrial signal amplitude > 3 mV seems to identify those patients with a lower risk of developing atrial fibrillation.

摘要

背景

由于预期寿命较短且存在房颤风险,老年患者的双腔起搏(DDD)仍是一个有争议的问题。本研究的目的是:1)评估累积生存率及能改变生存率的事件;2)评估窦性心律的稳定性;3)试图识别DDD植入后发生永久性房颤风险较高的患者。我们在植入时评估了临床、电生理和起搏参数。

方法

我们回顾性研究了一组连续的135例年龄大于80岁且在过去十年中接受DDD治疗的患者。

结果

在DDD植入后的评估时(平均33.51±27.10个月,范围4 - 148个月),72%的患者仍存活。96例(7l%)患者记录到窦性心律(A组)。39例(29%)患者(B组)在平均28.56±30.9个月(范围1 - 125个月)后发生房颤。与A组相比,B组右心房腔内信号幅度较低(分别为2.6±1.16 mV和3.27±1.91 mV)。两组的起搏和感知房室延迟无统计学差异。发生房颤的患者最低心率较高(A组和B组分别为64.53±7.7次/分钟和67.7±5.72次/分钟,p = 0.02)。B组患者植入前房颤发作率较高。两组病态窦房结疾病和房室结疾病的发生率相似。

结论

在老年患者中,DDD的益处可在房颤发生前长期维持。DDD植入前的房颤发作,除单纯窦房功能障碍外,可预测永久性房颤的发生。永久性房颤似乎并未降低预期寿命。较高的最低心率似乎不能预防房颤。记录到右心房信号幅度>3 mV的能力似乎可识别那些发生房颤风险较低的患者。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验