Matusik Paweł, Woznica Natalia, Lelakowsk Jacek
Uniwersytet Jagielloński, Collegium Medicum, Studenckie Koło Naukowe przy Klinice Elektrokardiologii.
Pol Merkur Lekarski. 2010 May;28(167):345-9.
Atrial fibrillation (AF) is a frequent problem of patients with pacemakers, and depends not only on disease but also on stimulation method. The aim of the study was to estimate the prevalence of AF before and after pacemaker implantation as well as to assess the influence of VVI and DDD cardiac pacing on onset of AF in patients with complete atrioventricularblock (AVB).
We included 155 patients controlled between 2000 and 2008 in Pacemaker Clinic because of AVB III degree, treated with VVI or DDD pacemaker implantation. Information about the health status of the patients was gathered from medical documentation and analysis of clinical ambulatory electrocardiograms.
The study group comprised of 68 women and 87 men, mean age 68.7 +/- 13.9 years during implantation. 69% of patients had VVI pacemaker. There were 72.3% of patients with sinus rhythm before pacemaker implantation. During follow-up 4 +/- 2.8 years in 19.6% cases onset of atrial fibrillation de novo was diagnosed (in 31.3% in VVI mode vs. 2.2% in DDD mode; p = 0.00014). Mean time to AF since implantation was approximately 2.5 years. In VVI group (21 persons) amounted 32.1 months, while in 1 patient with DDD pacemaker 18 months. Between group with AF after implantation and with sinus rhythm preserved there was no statistically significant difference in age or gender (p = 0.89512 and p = 0.1253, respectively). Prevalence of atrial fibrillation after pacemaker implantation increased to 40%.
Atrial fibrillation is frequent in patients before and after pacemaker implantation, especially in patients stimulated in VVI mode. Major possibility of atrial fibrillation onset after pacemaker implantation should result in more attention during routine ECG examination.
心房颤动(AF)是起搏器植入患者常见的问题,不仅取决于疾病,还取决于刺激方式。本研究的目的是评估起搏器植入前后AF的患病率,并评估VVI和DDD心脏起搏对完全性房室传导阻滞(AVB)患者AF发作的影响。
我们纳入了2000年至2008年期间在起搏器诊所因III度AVB接受VVI或DDD起搏器植入治疗的155例患者。从医疗记录和临床动态心电图分析中收集患者的健康状况信息。
研究组包括68名女性和87名男性,植入时平均年龄为68.7±13.9岁。69%的患者植入了VVI起搏器。起搏器植入前72.3%的患者为窦性心律。在4±2.8年的随访期间,19.6%的病例被诊断为新发心房颤动(VVI模式下为31.3%,DDD模式下为2.2%;p = 0.00014)。自植入以来发生AF的平均时间约为2.5年。VVI组(21人)为32.1个月,而1例DDD起搏器患者为18个月。植入后发生AF的组与窦性心律保留组之间在年龄或性别上无统计学显著差异(分别为p = 0.89512和p = 0.1253)。起搏器植入后心房颤动的患病率增至40%。
心房颤动在起搏器植入前后的患者中很常见,尤其是在VVI模式刺激的患者中。起搏器植入后发生心房颤动的可能性较大,这应导致在常规心电图检查中给予更多关注。