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[马任加大学医院中心宫颈阴道病变细胞学诊断的价值与局限性:465例病例]

[Value and limits of cytology in the diagnosis of cervico-vaginal lesions at the Mahajanga University Hospital Center: 465 cases].

作者信息

Ravolamanana Ralisata L, Randrianjafisamindrakotroka N S, Rakoto E B, Ranaivozanany A

机构信息

Centre Hospitalier Universitaire de Mahajanga, 401 Mahajanga, Madagascar.

出版信息

Arch Inst Pasteur Madagascar. 1999;65(1-2):120-3.

Abstract

Cervix neoplasms are the most frequent of female neoplasms in Madagascar. The authors reported a prospective study carried out at the Hospital Center of the University of Mahajanga for ten months (January-October 1993). 500 patients were investigated. 465 results of cervix and vaginal smears were considered. The Bethesda group classification was used to interpret lesions. 333 specific pathological lesions were listed. Bacterial infections and trichomoniasis were their principal causes. 4 cases were presumed as human papillomavirus condylomata. 39 SIL low-grade and 24 SIL high-grade were detected. 5 cervix neoplasms were diagnosed. Only few patients had consultation to perform cervix and vaginal smears because these exams are expensive. It may be an explication to the chronicity of lesions, a favourising factor of cancer. The role of viruses, especially human papillomavirus, in the development of cervix neoplasms is mentioned. The authors conclude that the low number of cervix neoplasms they founded is misleading. Cervix neoplasms are the first female cancers in Madagascar. A systematic surveillance of all female genitalia diseases must be programed. While its settling, cervix neoplasms control must be centred on Information--Education--Communication.

摘要

宫颈癌是马达加斯加女性肿瘤中最常见的。作者报告了在马任加大学医院中心进行的为期十个月(1993年1月至10月)的前瞻性研究。对500名患者进行了调查。考虑了465例宫颈和阴道涂片结果。采用贝塞斯达分类法对病变进行解释。列出了333种特定的病理病变。细菌感染和滴虫病是其主要原因。4例被推测为人乳头瘤病毒湿疣。检测到39例低级别鳞状上皮内病变和24例高级别鳞状上皮内病变。诊断出5例宫颈癌。只有少数患者因这些检查费用昂贵而前来进行宫颈和阴道涂片检查。这可能是病变慢性化的一个原因,是癌症的一个促发因素。文中提到了病毒,尤其是人乳头瘤病毒在宫颈癌发生发展中的作用。作者得出结论,他们发现的宫颈癌病例数较少具有误导性。宫颈癌是马达加斯加女性的首要癌症。必须规划对所有女性生殖器疾病进行系统监测。在实施过程中,宫颈癌控制必须以信息 - 教育 - 沟通为核心。

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