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经颅磁刺激:神经生理学应用与安全性

Transcranial magnetic stimulation: neurophysiological applications and safety.

作者信息

Anand Sulekha, Hotson John

机构信息

Department of Biological Sciences, San Jose State University, One Washington Square, San Jose, CA 95192-0100, USA.

出版信息

Brain Cogn. 2002 Dec;50(3):366-86. doi: 10.1016/s0278-2626(02)00512-2.

DOI:10.1016/s0278-2626(02)00512-2
PMID:12480484
Abstract

TMS is a non-invasive tool for measuring neural conduction and processing time, activation thresholds, facilitation and inhibition in brain cortex, and neural connections in humans. It is used to study motor, visual, somatosensory, and cognitive functions. TMS does not appear to cause long-term adverse neurological, cardiovascular, hormonal, motor, sensory, or cognitive effects in healthy subjects. Single-pulse (<1Hz) TMS is safe in normal subjects. High frequency, high-intensity repetitive TMS (rTMS) can elicit seizures even in normal subjects. Safety guidelines for using rTMS have been published.

摘要

经颅磁刺激(TMS)是一种用于测量人类神经传导和处理时间、激活阈值、大脑皮层的易化和抑制以及神经连接的非侵入性工具。它用于研究运动、视觉、躯体感觉和认知功能。在健康受试者中,TMS似乎不会引起长期的不良神经、心血管、激素、运动、感觉或认知影响。单脉冲(<1Hz)TMS对正常受试者是安全的。高频、高强度重复经颅磁刺激(rTMS)即使在正常受试者中也可诱发癫痫发作。已发布了使用rTMS的安全指南。

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Transcranial magnetic stimulation: neurophysiological applications and safety.经颅磁刺激:神经生理学应用与安全性
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Low frequency repetitive transcranial magnetic stimulation to the right dorsolateral prefrontal cortex engages thalamus, striatum, and the default mode network.对右侧背外侧前额叶皮层进行低频重复经颅磁刺激会激活丘脑、纹状体和默认模式网络。
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