Hafiz S, Hafiz A N, Ali L, Chughtai A S, Memon B, Ahmed A, Hussain S, Sarwar G, Mughal T, Siddiqui S J, Awan A, Zaki K, Fareed A
Mid-East Medical Center, Karachi.
J Pak Med Assoc. 2002 Jul;52(7):312-5.
To determine the frequency of Methicillin resistance Staphylococcus aureus infection in major cities of Pakistan.
Various laboratories of the country with one as the central Laboratory.
Seven hundred and ninety two consecutive clinical isolates of Staphylococcus aureus were collected from 8 laboratories all over Pakistan i.e. Karachi, Peshawar, Lahore, Sukkhur, Islamabad, Quetta, and Mirpur, Azad Kashmir. Antibiotic sensitivity was done by Kirby Bauer disc diffusion method and MIC of Vancomycin was determined by 'E' test.
Forty two percent of the isolates were found to be Methicillin resistant staphylococcus aureus (MRSA) while no Vancomycin resistance was encountered.
Methicillin resistant Staphylococcus aureus (MRSA) are seen in the local population with frequencies varying between 2-61% highest incidence is seen in the major cities of the country. Fortunately no Vancomycin resistant Staphylococcus has been isolated from any of the major cities.
确定巴基斯坦主要城市中耐甲氧西林金黄色葡萄球菌感染的发生率。
该国的多个实验室，其中一个为中心实验室。
从巴基斯坦各地的8个实验室（即卡拉奇、白沙瓦、拉合尔、苏库尔、伊斯兰堡、奎达和阿扎德克什米尔的米尔布尔）收集了792株连续的金黄色葡萄球菌临床分离株。采用 Kirby Bauer 纸片扩散法进行药敏试验，并用 “E” 试验测定万古霉素的最低抑菌浓度（MIC）。
发现42% 的分离株为耐甲氧西林金黄色葡萄球菌（MRSA），未发现对万古霉素耐药的情况。
在当地人群中可见耐甲氧西林金黄色葡萄球菌（MRSA），发生率在2% 至61% 之间，该国主要城市的发生率最高。幸运的是，在任何一个主要城市均未分离出耐万古霉素金黄色葡萄球菌。
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