Shizawa Ryoichi, Nagahori Yutaka, Kumamoto Nobufumi, Yamamoto Harumi, Takeda Kazunaga, Hamaguchi Youhei, Fukushima Tadao, Yamamoto Masayoshi, Mogaki Masatoshi, Fukasawa Shingo, Eguchi Kazuya, Kawahara Masaki, Nagahori Kaoru, Hosoi Hideo, Ohara Takeshi
Dept. of Surgery, Yokosuka Kyousai Hospital.
Gan To Kagaku Ryoho. 2002 Nov;29(12):2092-5.
We performed hepatic arterial infusion (HAI) chemotherapy for 4 patients with advanced gastric cancer who had undergone curative resection except for liver metastasis. The main antineoplastic drugs were 5-fluorouracil (5-FU), mitomycin C (MMC) and cisplatin (CDDP). A catheter was inserted into the hepatic artery by interventional radiological techniques in 3 patients and operatively in 1 patient. The response rate for 4 patients was 75% (CR2, PR1, PD1). The adverse events were Grade 3/4 nausea and/or vomiting in 2 cases. The HAI chemotherapy was effective and useful for patients with advanced gastric cancer who had no unresectable lesions except for liver metastasis.