Kurihara Akiharu, Nakazaki Haruhiro, Watanabe Masashi, Hasebe Yukinori, Takita Wataru, Seo Akira, Takata Masashi, Kobayashi Kazuo, Teramoto Tatsuo, Hirano Keihachiro
First Dept. of Surgery, Toho University School of Medicine.
Gan To Kagaku Ryoho. 2002 Nov;29(12):2104-7.
Hepatectomy and intraarterial chemotherapy for liver metastasis from colorectal cancer have been performed in our department. Intraarterial infusion chemotherapy has also been performed for unresectable liver metastasis. One hundred twenty-seven cases of liver metastasis from colorectal cancer were studied. The cases were divided into groups according to radicability of the original colorectal cancer, whether or not hepatectomy was performed, and whether or not they received intraarterial chemotherapy. Group I is cur C of origin. Group II is cur A or B without hepatectomy. Group III is cur A or B with hepatectomy. Each group was divided into a group without intraarterial chemotherapy (A) and a group with it (B). IA 23 cases, IB 13 cases, IIA 14 cases, IIB 21 cases, IIIA 28 cases, and IIIB 28 cases. The survival rate of group III was better than that of group II. The survival rate of group II was better than that of group I. There was no significant difference in survival rates between IA and IB. The survival rate of group IIB was significantly better than that of group IIA. The survival rate of group IIIB was significantly better than that of group III A. Hepatectomy and intraarterial chemotherapy after hepatectomy for liver metastasis from colorectal cancer were effective.
我科已开展了针对结直肠癌肝转移的肝切除术及肝动脉化疗。对于无法切除的肝转移灶，也进行了肝动脉灌注化疗。对127例结直肠癌肝转移病例进行了研究。这些病例根据原发结直肠癌的可切除性、是否进行肝切除术以及是否接受肝动脉化疗进行分组。第一组为原发灶可根治性切除C期。第二组为可根治性切除A或B期但未行肝切除术。第三组为可根治性切除A或B期且行肝切除术。每组又分为未接受肝动脉化疗的组（A）和接受肝动脉化疗的组（B）。IA组23例，IB组13例，IIA组14例，IIB组21例，IIIA组28例，IIIB组28例。第三组的生存率优于第二组。第二组的生存率优于第一组。IA组和IB组的生存率无显著差异。IIB组的生存率显著优于IIA组。IIIB组的生存率显著优于IIIA组。结直肠癌肝转移行肝切除术及肝切除术后的肝动脉化疗是有效的。
