Weigert Monika, Kaali Steven G, Kulin Sandor, Feichtinger Wilfried
J Assist Reprod Genet. 2002 Nov;19(11):539-40. doi: 10.1023/a:1020968020504.
Our objective was to investigate the lunar influence on IVF-ET outcomes.
Between 1992 and 1999 we have completed 7572 preprogrammed IVF-ET treatment cycles with the same stimulation protocol in two outpatient units. (Vienna, Austria and Budapest, Hungary) Multiple regression (SAS; proc Logistic) and two separate analyses were performed on pregnancy rates using a harmonic sinoidal trend based on the synodic and anomalistic lunar cycles respectively.
The overall pregnancy rate was 30.9%. The amplitude of harmonic sinoidal, trend for the synodic lunar cycles was chi2 = 1.63,2d.f., p = 0.44 and chi2 = 6.27,2d.f., p = 0.044 for the anomalistic moon periods. For the anomalistic lunar months the amplitude of harmonic sinoidal trend was borderline in terms of higher pregnancy rates with the moon in Perigee.
The cause of seasonal changes in IVF-ET outcomes is probably very complex. Our results indicate that lunar influence may only be one of the contributing factors. Further studies are needed to clarify unexplained fluctuations of pregnancy outcomes.
我们的目标是研究月球对体外受精 - 胚胎移植(IVF - ET)结果的影响。
1992年至1999年间,我们在两个门诊单位(奥地利维也纳和匈牙利布达佩斯)完成了7572个采用相同刺激方案的预编程IVF - ET治疗周期。分别基于朔望月和近点月周期,使用谐波正弦趋势对妊娠率进行多元回归分析(SAS;proc Logistic)和两项独立分析。
总体妊娠率为30.9%。朔望月周期的谐波正弦趋势幅度为χ² = 1.63,自由度为2,p = 0.44;近点月周期的χ² = 6.27,自由度为2,p = 0.044。对于近点月,当月球处于近地点时,谐波正弦趋势幅度在较高妊娠率方面处于临界状态。
IVF - ET结果的季节性变化原因可能非常复杂。我们的结果表明,月球影响可能只是促成因素之一。需要进一步研究以阐明妊娠结果中无法解释的波动。